Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8075152 | 0.93 | TK1 (0.44) | TK1RNASE1 | |
| SCHEMBL551408 | 0.84 | TK1 (0.49) | TK1RNASE1 | |
| SCHEMBL9753627 | 0.79 | TK1 (0.48) | TK1 | |
| SCHEMBL8177256 | 0.76 | TK1 (0.34) | TK1 | |
| SCHEMBL8329365 | 0.76 | LMNA (0.44) | TK1 | |
| SCHEMBL1764557 | 0.75 | TK1 (0.65) | TK1 | |
| SCHEMBL4077432 | 0.75 | TK1 (0.46) | TK1RNASE1 | |
| SCHEMBL9084280 | 0.75 | TK1 (0.46) | TK1 | |
| SCHEMBL1827367 | 0.74 | TK1 (0.44) | TK1 | |
| SCHEMBL7780995 | 0.74 | TK1 (0.45) | TK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030064483-A1 | Method of nucleic acid sequencing | DUKE UNIVERSITY. | 2003-04-03 | — | — | US | disclosed |
| US-6376178-B1 | INTRODUCING INTO CELL DNA SEQUENCE ENCODING PROTEIN, WHICH DNA SEQUENCE COMPRISES BORONATED NUCLEOTIDE, UNDER CONDITIONS SUCH THAT DNA SEQUENCE IS EXPRESSED AND PROTEIN THEREBY PRODUCED | DUKE UNIVERSITY | 2002-04-23 | — | — | US | disclosed |
| US-5859231-A | SYNTHESIZING AN OLIGONUCLEOTIDE COMPRSING AN INTERNUCLEOTIDE H-PHOSPHATE DIESTER LINKAGE, REACTING DIESTER WITH BIS/TRIMETHYLSILYL/ACETAMIDE OR HALOGENATING AGENT TO FORM TRIESTER, BORONATING WITH AMINE BORANE; REACTING WITH AMMONIA | DUKE UNIVERSITY (US) | 1999-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030064483-A1 | Method of nucleic acid sequencing | POLRMT, RNGTT, POLN | TK1 209/4885RNASE1 20/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.