Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | DNM2 | P50570 | 9/20 | 0.44 |
| ▸ | KCNH3 | Q9ULD8 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8070620 | 0.90 | DNM2 (0.49) | KMT2ADNM2KCNH3HTTMAPT | |
| SCHEMBL17563604 | 0.87 | HTT (0.42) | HTTMAPT | |
| SCHEMBL18680442 | 0.85 | CYP1A2 (0.41) | KMT2AHTTMAPT | |
| SCHEMBL14869524 | 0.85 | KCNH3 (0.56) | KMT2ADNM2KCNH3HTTMAPT | |
| SCHEMBL17563602 | 0.83 | CXCR2 (0.40) | KMT2ADNM2KCNH3HTTMAPT | |
| SCHEMBL15403287 | 0.82 | KMT2A (0.64) | KMT2ADNM2KCNH3SLC29A1 | |
| SCHEMBL8077020 | 0.82 | KMT2A (0.51) | KMT2ADNM2KCNH3MAPT | |
| SCHEMBL8077182 | 0.82 | KMT2A (0.51) | KMT2ADNM2KCNH3HTTMAPT | |
| SCHEMBL17576150 | 0.81 | HSP90AA1 (0.42) | HTTMAPT | |
| SCHEMBL18466906 | 0.81 | HTT (0.38) | HTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0648755-B1 | Improved process for the preparation of 2,4-di(alkylamino)-6-alkylthio-s-triazines and 2-alkylamino-4,6-di(alkylthio)-s-triazines | CIBA SC HOLDING AG (CH) | 2000-08-02 | — | — | EP | disclosed |
| US-5420274-A | Process for the preparation of 2,4-di(alkylamino)-6-alkylthio-s-triazines | CIBA-GEIGY CORPORATION (US) | 1995-05-30 | — | — | US | disclosed |
| EP-0648755-A1 | Improved process for the preparation of 2,4-Di(alkylamino)-6-alkylthio-s-triazines | CIBA-GEIGY AG (CH) | 1995-04-19 | — | — | EP | disclosed |