Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 4/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HSD17B1 | P14061 | 5/20 | 0.39 |
| ▸ | HSD17B2 | P37059 | 5/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | CASP3 | P42574 | 2/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NSD2 | O96028 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10012179 | 0.80 | ACHE (0.46) | ACHETDP1TP53SIGMAR1ALDH1A1 | |
| SCHEMBL977663 | 0.75 | ACHE (0.58) | ACHETDP1TP53SIGMAR1ALDH1A1 | |
| SCHEMBL9216448 | 0.75 | RAB9A (0.42) | ACHETP53SIGMAR1ALDH1A1HSD17B1 | |
| SCHEMBL29381010 | 0.73 | ALDH1A1 (0.56) | ACHETDP1SIGMAR1ALDH1A1MAPK1 | |
| SCHEMBL29692933 | 0.73 | ACHE (0.55) | ACHETDP1TP53SIGMAR1ALDH1A1 | |
| SCHEMBL134721 | 0.73 | ACHE (0.55) | ACHETDP1TP53SIGMAR1ALDH1A1 | |
| SCHEMBL1697445 | 0.73 | ACHE (0.55) | ACHETDP1SIGMAR1ALDH1A1MAPK1 | |
| SCHEMBL11366275 | 0.73 | ALDH1A1 (0.48) | ACHETDP1ALDH1A1MAPK1NPC1 | |
| SCHEMBL12879 | 0.73 | ALDH1A1 (0.56) | ACHETDP1SIGMAR1ALDH1A1MAPK1 | |
| SCHEMBL11367138 | 0.73 | ALDH1A1 (0.37) | TDP1ALDH1A1HSD17B1HSD17B2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640591-B1 | Azomethine derivatives as UV light absorbers | ORIENT CHEMICAL IND (JP) | 2000-11-02 | — | — | EP | disclosed |
| EP-0640591-A1 | Azomethine derivatives as UV light absorbers | ORIENT CHEMICAL INDUSTRIES, LTD. (JP) | 1995-03-01 | — | — | EP | disclosed |
| US-4276295-A | VASODILATORS, HYPOTENSIVE, ANTIATHEROSCLEROTIC | Ishikawa, Masayuki (JP) | 1981-06-30 | — | — | US | disclosed |