Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 2/20 | 0.42 |
| ▸ | DAO | P14920 | 1/20 | 0.42 |
| ▸ | MET | P08581 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | CTSD | P07339 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7074802 | 0.88 | HDAC4 (0.53) | DGAT1LMNAMAPTALDH1A1TSHR | |
| SCHEMBL8080502 | 0.83 | LMNA (0.44) | DGAT1LMNAMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL8076011 | 0.82 | LMNA (0.51) | DGAT1LMNAMAPTALDH1A1POLB | |
| SCHEMBL7069910 | 0.77 | MGLL (0.52) | DGAT1LMNATSHRTHRBHDAC4 | |
| SCHEMBL7074627 | 0.77 | TSHR (0.57) | DGAT1LMNAMAPTALDH1A1TSHR | |
| SCHEMBL7074862 | 0.76 | DGAT1 (0.53) | DGAT1LMNAMAPTALDH1A1TSHR | |
| SCHEMBL7069975 | 0.74 | GAA (0.60) | DGAT1LMNAMAPTALDH1A1TSHR | |
| SCHEMBL12747582 | 0.74 | L3MBTL1 (0.62) | MAPTL3MBTL1TSHRPOLBTP53 | |
| SCHEMBL7075151 | 0.73 | HDAC4 (0.49) | DGAT1LMNAMAPTALDH1A1THRB | |
| SCHEMBL7070017 | 0.73 | DGAT1 (0.50) | DGAT1LMNAMAPTALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1025086-A1 | BENZAMIDINE DERIVATIVES AS FACTOR XA INHIBITORS | MERCK PATENT GmbH (DE) | 2000-08-09 | — | — | EP | disclosed |
| WO-1999016751-A1 | BENZAMIDINE DERIVATIVES AS FACTOR XA INHIBITORS | MERCK PATENT GMBH (DE) | 1999-04-08 | — | — | WO | disclosed |