SCHEMBL8076428

SCHEMBL8076428

Cc1ccc(S(=O)(=O)O)cc1C1CCCC1C

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.37
LMNA P02545 3/20 0.37
MAPT P10636 2/20 0.37
HTT P42858 1/20 0.37
CA1 P00915 3/20 0.36
CA2 P00918 3/20 0.36
CA12 O43570 2/20 0.36
CA7 P43166 2/20 0.36
CA14 Q9ULX7 2/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
PKM P14618 1/20 0.36
ACHE P22303 1/20 0.36
GAA P10253 1/20 0.35
CNR1 P21554 1/20 0.35
CNR2 P34972 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
MCOLN3 Q8TDD5 1/20 0.35
SNCA P37840 1/20 0.34
JAK2 O60674 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL658620 0.97 ALDH1A1 (0.40) ALDH1A1LMNAMAPTHTTCA1
SCHEMBL780174 0.85 ALDH1A1 (0.38) ALDH1A1LMNAMAPTCA1CA2
SCHEMBL7100553 0.84 ALDH1A1 (0.39) ALDH1A1LMNAMAPTCA1CA2
SCHEMBL9101015 0.80 TDP1 (0.39) ALDH1A1MAPTMEN1KMT2APKM
SCHEMBL8763566 0.80 ALDH1A1 (0.43) ALDH1A1LMNAMAPTHTTCA1
SCHEMBL29104732 0.79 CA1 (0.41) ALDH1A1LMNAMAPTHTTCA1
SCHEMBL656155 0.78 PTGS2 (0.42) ALDH1A1LMNAMAPTHTTCA1
SCHEMBL778787 0.77 ALDH1A1 (0.35) ALDH1A1LMNAMAPTHTTCA1
SCHEMBL778058 0.76 CA1 (0.36) ALDH1A1LMNAMAPTHTTCA1
SCHEMBL8076430 0.75 NOS3 (0.41) CA1CA2MEN1KMT2AACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0493606-B1 HETEROCYCLE-SUBSTITUTED BENZENE DERIVATIVE, PRODUCTION THEREOF, AND HERBICIDE CONTAINING THE SAME AS ACTIVE INGREDIENT SAGAMI CHEM RES (JP) 2000-10-18 EP disclosed
EP-1006105-A1 Benzene derivatives SAGAMI CHEMICAL RESEARCH CENTER (JP) 2000-06-07 EP disclosed
US-5424277-A An N-substituted-3,4,5,6-tetrahydrophthalimide derivative characterized by having a cycloalkoxy group at the 5-position of the phenyl ring on the nitrogen SAGAMI CHEMICAL RESEARCH CENTER (JP) 1995-06-13 US disclosed
EP-0493606-A1 HETEROCYCLE-SUBSTITUTED BENZENE DERIVATIVE, PRODUCTION THEREOF, AND HERBICIDE CONTAINING THE SAME AS ACTIVE INGREDIENT SAGAMI CHEMICAL RESEARCH CENTER (JP) 1992-07-08 EP disclosed