Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 5/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL658620 | 0.83 | ALDH1A1 (0.40) | TDP1ALDH1A1MAPTKMT2APKM | |
| SCHEMBL7100553 | 0.82 | ALDH1A1 (0.39) | TDP1ALDH1A1MAPTKMT2ATSHR | |
| SCHEMBL780174 | 0.81 | ALDH1A1 (0.38) | TDP1ALDH1A1MAPTKMT2ATSHR | |
| SCHEMBL8076428 | 0.80 | ALDH1A1 (0.37) | TDP1ALDH1A1MAPTKMT2APKM | |
| SCHEMBL656155 | 0.80 | PTGS2 (0.42) | TDP1ALDH1A1MAPTKMT2ATSHR | |
| SCHEMBL8763566 | 0.78 | ALDH1A1 (0.43) | TDP1ALDH1A1MAPTPKMTHRB | |
| SCHEMBL9101004 | 0.76 | EPHX2 (0.37) | ALDH1A1KMT2ATSHRMEN1MCOLN3 | |
| SCHEMBL29104732 | 0.75 | CA1 (0.41) | TDP1ALDH1A1MAPTKMT2ATSHR | |
| SCHEMBL9100947 | 0.71 | PPIA (0.36) | ALDH1A1MAPTKMT2ATSHRMEN1 | |
| SCHEMBL16461465 | 0.70 | KMT2A (0.38) | ALDH1A1MAPTKMT2ATSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5489501-A | MIXTURES OF TWO COORDINATION COMPOUNDS WHICH REACT TO FORM NEW COORDINATION COMPOUND WHILE CAUSING VISIBLE COLOR CHANGES | RICOH COMPANY, LTD. (JP) | 1996-02-06 | — | — | US | disclosed |
| US-5446011-A | Imagewise coloring when heating; mixture of n-substituted indole, aromatic polyhydroxy compound, carbonyl compound and an acid | RICOH COMPANY, LTD. (JP) | 1995-08-29 | — | — | US | disclosed |