Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | USP2 | O75604 | 2/20 | 0.31 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.31 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.31 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8065777 | 0.71 | PGAM1 (0.38) | MAPTLMNASMN1; SMN2HTTMEN1 | |
| SCHEMBL8076780 | 0.71 | SMN1; SMN2 (0.37) | MAPTLMNASMN1; SMN2HSP90AA1HTT | |
| SCHEMBL8076772 | 0.71 | SMN1; SMN2 (0.37) | MAPTLMNASMN1; SMN2HSP90AA1HTT | |
| SCHEMBL10446577 | 0.71 | TTR (0.51) | MAPTLMNASMN1; SMN2HSP90AA1HTT | |
| SCHEMBL3839152 | 0.70 | NFE2L2 (0.42) | SMN1; SMN2KMT2AALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL30528698 | 0.70 | MAPT (0.62) | MAPTLMNASMN1; SMN2HTTHIF1A | |
| SCHEMBL29050080 | 0.70 | MAPT (0.62) | MAPTLMNASMN1; SMN2HTTHIF1A | |
| SCHEMBL24194431 | 0.68 | TOP1 (0.64) | MAPTLMNAHTTHIF1AMEN1 | |
| SCHEMBL550665 | 0.68 | TDP1 (0.39) | MAPTLMNASMN1; SMN2HTTMEN1 | |
| SCHEMBL27635813 | 0.67 | PTGS2 (0.52) | MAPTLMNAHTTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6033826-A | POLYHYDROXYSTYRENE DERIVATIVE CONTAINING AN ACETAL OR KETAL GROUP WHICH CAN EASILY BE ELIMINATED IN THE PRESENCE OF AN ACID IN THE MOLECULE AND HAVING A VERY NARROW MOLECULAR WEIGHT DISTRIBUTION GIVES A RESIST MATERIAL | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 2000-03-07 | — | — | US | disclosed |