Sugi Predict

Sugi Predict / Compounds / SCHEMBL550665

SCHEMBL550665

SCHEMBL550665

CS(=O)(=O)Oc1cccc2c1C(=O)OC2=O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TDP1 Q9NUW8 2/20 0.39
▸ ALOX15 P16050 1/20 0.39
▸ ALDH1A1 P00352 8/20 0.38
▸ MAPT P10636 7/20 0.38
▸ SMN1; SMN2 Q16637 5/20 0.38
▸ KDM4E B2RXH2 4/20 0.38
▸ RAB9A P51151 4/20 0.38
▸ NPC1 O15118 3/20 0.38
▸ HPGD P15428 3/20 0.38
▸ CYP1A2 P05177 2/20 0.38
▸ CYP3A4 P08684 1/20 0.38
▸ CYP2C19 P33261 1/20 0.38
▸ TYMS P04818 1/20 0.37
▸ KMT2A Q03164 6/20 0.36
▸ MEN1 O00255 4/20 0.36
▸ LMNA P02545 3/20 0.35
▸ TOP1 P11387 1/20 0.35
▸ APAF1 O14727 1/20 0.35
▸ MITF O75030 1/20 0.35
▸ HTT P42858 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3376352 0.83 TDP1 (0.36) TDP1ALOX15ALDH1A1MAPTSMN1; SMN2
SCHEMBL552117 0.79 IDO1 (0.34) TDP1ALDH1A1MAPTSMN1; SMN2KDM4E
SCHEMBL552118 0.79 IDO1 (0.34) TDP1ALDH1A1MAPTSMN1; SMN2KDM4E
SCHEMBL3374741 0.79 DRD2 (0.44) TDP1ALOX15ALDH1A1MAPTSMN1; SMN2
SCHEMBL382674 0.78 TOP1 (0.56) TDP1ALOX15ALDH1A1MAPTSMN1; SMN2
SCHEMBL30610021 0.78 TOP1 (0.56) TDP1ALOX15ALDH1A1MAPTSMN1; SMN2
SCHEMBL9663235 0.78 TDP1 (0.44) TDP1ALOX15ALDH1A1MAPTSMN1; SMN2
SCHEMBL261809 0.77 TDP1 (0.48) TDP1ALOX15ALDH1A1MAPTSMN1; SMN2
SCHEMBL31228169 0.77 TDP1 (0.48) TDP1ALOX15ALDH1A1MAPTSMN1; SMN2
SCHEMBL8948094 0.77 TDP1 (0.48) TDP1ALOX15ALDH1A1MAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108601353-B Bactericidal composition 高文作物保护公司 2024-04-05 — — CN disclosed
US-11903387-B2 Fungicidal composition GOWAN COMPANY, L.L.C. (US) 2024-02-20 — — US disclosed
US-20210045386-A1 FUNGICIDAL COMPOSITION BANK OF AMERICA, N.A., AS ADMINISTRATIVE AGENT 2021-02-18 — — US disclosed
EP-3181563-B1 CONDENSED 11-MEMBER RING COMPOUND AND AGRICULTURE AND HORTICULTURAL FUNGICIDE COMPRISING SAME SDS BIOTECH CORP (JP) 2019-02-06 — — EP disclosed
EP-3415008-A1 GERMICIDAL COMPOSITION SDS Biotech K. K. (JP) 2018-12-19 — — EP disclosed
US-10104891-B2 Fused 11-membered compounds and agricultural/horticultural fungicides containing them SDS BIOTECH K.K. (JP) 2018-10-23 — — US disclosed
US-20180235225-A1 FUSED 11-MEMBERED COMPOUNDS AND AGRICULTURAL/HORTICULTURAL FUNGICIDES CONTAINING THEM BANK OF AMERICA, N.A., AS ADMINISTRATIVE AGENT 2018-08-23 — — US disclosed
US-9980487-B2 Fused 11-membered compounds and agricultural/horticultural fungicides containing them SDS BIOTECH K.K. (JP) 2018-05-29 — — US disclosed
US-20170231226-A1 FUSED 11-MEMBERED COMPOUNDS AND AGRICULTURAL/HORTICULTURAL FUNGICIDES CONTAINING THEM SDS BIOTECH K.K. (JP) 2017-08-17 — — US disclosed
EP-3181563-A1 CONDENSED 11-MEMBER RING COMPOUND AND AGRICULTURE AND HORTICULTURAL FUNGICIDE COMPRISING SAME SDS Biotech K. K. (JP) 2017-06-21 — — EP disclosed
WO-2006133823-A1 BENZANILIDES WITH INSECTICIDAL ACTIVITY BAYER CROPSCIENCE AG (DE) 2006-12-21 — — WO disclosed
EP-1727804-A1 N1 - ((PYRAZOL-1-YMETHYL) -2-METHYLPHENYL)- PHATALAMIDE DERIVATIVES AND RELATED COMPOUNDS INSECTICIDES Bayer CropScience Aktiengesellschaft (DE) 2006-12-06 — — EP disclosed
US-7132455-B2 Phthalamide derivatives BAYER CROPSCIENCE AG (DE) 2006-11-07 — — US disclosed
US-20060223872-A1 Insecticidal phthalamide derivatives BAYER CROPSCIENCE AG (DE) 2006-10-05 — — US disclosed
US-20060035967-A1 Novel phthalamide derivatives BAYER INTELLECTUAL PROPERTY GMBH (DE) 2006-02-16 — — US disclosed
EP-1606271-A1 INSECTICIDAL PHTHALAMIDE DERIVATIVES Bayer CropScience AG (DE) 2005-12-21 — — EP disclosed
WO-2005095351-A1 N1 - ((PYRAZOL-1-YMETHYL) -2-METHYLPHENYL)- PHATALAMIDE DERIVATIVES AND RELATED COMPOUNDS INSECTICIDES BAYER CROPSCIENCE AG (DE) 2005-10-13 — — WO disclosed
EP-1517886-A1 NOVEL PHTHALAMIDE DERIVATIVES Bayer CropScience AG (DE) 2005-03-30 — — EP disclosed
WO-2004080984-A1 INSECTICIDAL PHTHALAMIDE DERIVATIVES BAYER CROPSCIENCE AG (DE) 2004-09-23 — — WO disclosed
WO-2004000796-A1 NOVEL PHTHALAMIDE DERIVATIVES BAYER CROPSCIENCE AG (DE) 2003-12-31 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170231226-A1 FUSED 11-MEMBERED COMPOUNDS AND AGRICULTURAL/HORTICULTURAL FUNGICIDES CONTAINING THEM CYP51A1, CYP4Z1, ERG28 TDP1 2514/4885ALOX15 2831/4885ALDH1A1 1607/4885
US-20060035967-A1 Novel phthalamide derivatives HDAC1, HDAC2, CRY1 TDP1 3715/4885ALOX15 4156/4885ALDH1A1 1071/4885
US-20060223872-A1 Insecticidal phthalamide derivatives CRYAA, PRXL2A, H1-2 TDP1 3555/4885ALOX15 3530/4885ALDH1A1 1457/4885
US-20210045386-A1 FUNGICIDAL COMPOSITION CYP51A1, CYP4Z1, ERG28 TDP1 733/4885ALOX15 1462/4885ALDH1A1 430/4885
US-10104891-B2 Fused 11-membered compounds and agricultural/horticultural fungicides containing them CYP51A1, CYP4Z1, ERG28 TDP1 2514/4885ALOX15 2831/4885ALDH1A1 1607/4885
US-20180235225-A1 FUSED 11-MEMBERED COMPOUNDS AND AGRICULTURAL/HORTICULTURAL FUNGICIDES CONTAINING THEM CYP51A1, CYP4Z1, ERG28 TDP1 2514/4885ALOX15 2831/4885ALDH1A1 1607/4885
US-11903387-B2 Fungicidal composition CYP51A1, CYP4Z1, ERG28 TDP1 733/4885ALOX15 1462/4885ALDH1A1 430/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.