Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 3/20 | 0.46 |
| ▸ | NSD2 | O96028 | 1/20 | 0.45 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.44 |
| ▸ | EHMT2 | Q96KQ7 | 2/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | KMT5A | Q9NQR1 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8071856 | 0.89 | MGLL (0.47) | MGLLEHMT2MAPTPOLBLMNA | |
| SCHEMBL8061075 | 0.83 | EHMT2 (0.48) | NSD2DNMT3AEHMT2ALDH1A1KMT5A | |
| SCHEMBL8076826 | 0.83 | ADRA1A (0.56) | — | |
| SCHEMBL8076863 | 0.81 | ALDH1A1 (0.50) | MAPTPOLBLMNAALDH1A1HTT | |
| SCHEMBL8070274 | 0.79 | CCR4 (0.52) | EHMT2KMT5A | |
| SCHEMBL8071618 | 0.79 | DNMT1 (0.45) | NSD2DNMT3AEHMT2MAPTALDH1A1 | |
| SCHEMBL8077026 | 0.76 | ADRA1A (0.60) | — | |
| SCHEMBL8070244 | 0.71 | EHMT2 (0.52) | EHMT2 | |
| SCHEMBL20422061 | 0.71 | MAPT (0.45) | MAPTPOLBALDH1A1ITGB3ITGA2B | |
| SCHEMBL8071878 | 0.71 | GPR119 (0.56) | MAPTALDH1A1MEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6156758-A | Antibacterial quinazoline compounds | ISIS PHARMACEUTICALS, INC. (US) | 2000-12-05 | — | — | US | disclosed |