SCHEMBL8077101

SCHEMBL8077101

CCCC(CC(=O)ON1C(=O)CC(S(=O)(=O)O)C1=O)NC(=O)c1ccc(C(C)SSc2ccccn2)cc1

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TAS1R3 Q7RTX0 3/20 0.32
TAS1R1 Q7RTX1 3/20 0.32
KCNA5 P22460 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL321300 0.83 SMN1; SMN2 (0.35)
SCHEMBL17161322 0.83 RGS12 (0.31)
SCHEMBL5162779 0.81
SCHEMBL16491630 0.78 HDAC6 (0.35)
SCHEMBL2169209 0.77 LMNA (0.31)
SCHEMBL29427561 0.77 LMNA (0.31)
SCHEMBL15489464 0.76 NPC1 (0.36)
SCHEMBL900949 0.76 SMN1; SMN2 (0.36)
SCHEMBL7572269 0.74 HTR1A (0.36)
SCHEMBL15493502 0.74 SMN1; SMN2 (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1034303-A1 METHODS OF DETECTING POLYNUCLEOTIDE ANALYTES Diasorin International Inc. (US) 2000-09-13 EP disclosed
WO-1999028503-A1 METHODS OF DETECTING POLYNUCLEOTIDE ANALYTES DIASORIN INTERNATIONAL INC. (US) 1999-06-10 WO disclosed
WO-1999015897-A1 SUBTRACTIVE PROTEIN SCREENING FOR GENE IDENTIFICATION CHIRON CORPORATION (US) 1999-04-01 WO disclosed