⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17161322 | 0.83 | RGS12 (0.31) | — | |
| SCHEMBL8077101 | 0.81 | TAS1R3 (0.32) | — | |
| SCHEMBL5958158 | 0.81 | HDAC1 (0.33) | — | |
| SCHEMBL321300 | 0.79 | SMN1; SMN2 (0.35) | — | |
| SCHEMBL16491630 | 0.75 | HDAC6 (0.35) | — | |
| SCHEMBL7572269 | 0.74 | HTR1A (0.36) | — | |
| SCHEMBL2169209 | 0.73 | LMNA (0.31) | — | |
| SCHEMBL29427561 | 0.73 | LMNA (0.31) | — | |
| SCHEMBL15489464 | 0.72 | NPC1 (0.36) | — | |
| SCHEMBL900949 | 0.72 | SMN1; SMN2 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0942996-B8 | THROMBOLYTIC AGENTS WITH ANTITHROMBOTIC ACTIVITY | UNIV SOUTHERN CALIFORNIA (US) | 2007-02-21 | — | — | EP | claimed |
| EP-0942996-A1 | THROMBOLYTIC AGENTS WITH ANTITHROMBOTIC ACTIVITY | Diatide, Inc. (US) | 1999-09-22 | — | — | EP | claimed |
| WO-1998024917-A1 | THROMBOLYTIC AGENTS WITH ANTITHROMBOTIC ACTIVITY | DIATIDE, INC. (US) | 1998-06-11 | — | — | WO | claimed |
| US-5951981-A | A CROSSLINKED THROMBOLYTIC PROTEINASE, E.G. FIBROLASE FROM AGKISTRODOON CONTORTRIX CONFORTRIX VENOM, AND A BINDING PEPTIDE THAT BINDS AT THE SITE OF BLOOD CLOTS AND THROMBI; SIDE EFFECTS REDUCTION | DIATIDE, INC. (US) | 1999-09-14 | — | — | US | disclosed |