Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CCR3 | P51677 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.37 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.37 |
| ▸ | TACR1 | P25103 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7066523 | 0.90 | ALDH1A1 (0.41) | ALDH1A1P2RX7POLBFFAR1GRIN2B | |
| SCHEMBL7067269 | 0.88 | GPBAR1 (0.40) | CCR3ALDH1A1P2RX7GRIN2BPPARG | |
| SCHEMBL7066355 | 0.86 | FKBP1A (0.47) | ALDH1A1ACHE | |
| SCHEMBL7065723 | 0.84 | ALDH1A1 (0.46) | CHRM2ALDH1A1POLBHSD11B1TDP1 | |
| SCHEMBL7068394 | 0.80 | FKBP1A (0.51) | CHRM2 | |
| SCHEMBL6231716 | 0.79 | PKM (0.44) | CHRM2ALDH1A1POLBHSD11B1 | |
| SCHEMBL7068098 | 0.79 | PKM (0.44) | CHRM2ALDH1A1POLBHSD11B1 | |
| SCHEMBL6233365 | 0.79 | PKM (0.44) | CHRM2ALDH1A1POLBHSD11B1 | |
| SCHEMBL7062141 | 0.79 | FKBP1A (0.43) | — | |
| SCHEMBL7066363 | 0.79 | OPRM1 (0.44) | CHRM2ALDH1A1HSD11B1OPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114543-A | Process for producing optically active azetidine-2-carboxylic acid | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-09-05 | — | — | US | disclosed |