Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | CCR5 | P51681 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7067269 | 0.91 | GPBAR1 (0.40) | ALDH1A1GRIN2BTACR1SMN1; SMN2P2RX7 | |
| SCHEMBL8077137 | 0.90 | CHRM2 (0.42) | ALDH1A1GRIN2BPOLBTACR1SMN1; SMN2 | |
| SCHEMBL7066507 | 0.86 | FKBP1A (0.47) | SMN1; SMN2HPGD | |
| SCHEMBL7067280 | 0.83 | ALDH1A1 (0.45) | ALDH1A1KDM4EPOLBKMT2ASMN1; SMN2 | |
| SCHEMBL7068090 | 0.80 | ALDH1A1 (0.44) | ALDH1A1GRIN2BKDM4EMAPTTACR1 | |
| SCHEMBL7064586 | 0.80 | FKBP1A (0.48) | — | |
| SCHEMBL7064406 | 0.79 | P2RX7 (0.42) | ALDH1A1GRIN2BMEN1MAPTKMT2A | |
| SCHEMBL7064400 | 0.79 | FKBP1A (0.50) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL7062112 | 0.78 | ALDH1A1 (0.53) | ALDH1A1KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7066206 | 0.78 | FKBP1A (0.40) | ALDH1A1MEN1MAPTKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0827954-B1 | Process for producing optically active azetidine-2-carboxylic acid | SUMITOMO CHEMICAL CO (JP) | 2003-06-04 | — | — | EP | disclosed |
| US-6114543-A | Process for producing optically active azetidine-2-carboxylic acid | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-09-05 | — | — | US | disclosed |
| EP-0827954-A1 | Process for producing optically active azetidine-2-carboxylic acid | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1998-03-11 | — | — | EP | disclosed |