Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 5/20 | 0.43 |
| ▸ | MMP1 | P03956 | 4/20 | 0.43 |
| ▸ | MMP13 | P45452 | 4/20 | 0.43 |
| ▸ | MMP2 | P08253 | 4/20 | 0.43 |
| ▸ | MMP9 | P14780 | 3/20 | 0.43 |
| ▸ | MMP8 | P22894 | 3/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | MMP14 | P50281 | 2/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | MMP12 | P39900 | 1/20 | 0.36 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.35 |
| ▸ | MMP7 | P09237 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7002033 | 0.90 | MMP1 (0.55) | MMP3MMP1MMP13MMP2MMP9 | |
| SCHEMBL7001935 | 0.80 | MMP1 (0.46) | MMP3MMP1MMP13MMP2MMP9 | |
| SCHEMBL7000007 | 0.78 | MMP13 (0.66) | MMP3MMP1MMP13MMP2MMP9 | |
| SCHEMBL6998203 | 0.73 | MMP1 (0.50) | MMP3MMP1MMP13MMP2MMP9 | |
| SCHEMBL7991333 | 0.72 | MMP2 (0.40) | MMP3MMP1MMP13MMP2MMP9 | |
| SCHEMBL7143052 | 0.71 | MMP13 (0.45) | MMP3MMP1MMP13MMP2MMP9 | |
| SCHEMBL6997644 | 0.71 | MAPT (0.38) | MMP3MMP1MMP13MMP2MMP9 | |
| SCHEMBL7144631 | 0.70 | MMP13 (0.44) | MMP3MMP1MMP13MMP2MMP9 | |
| SCHEMBL6995889 | 0.69 | MMP1 (0.58) | MMP3MMP1MMP13MMP2MMP9 | |
| SCHEMBL6995105 | 0.69 | MMP1 (0.57) | MMP3MMP1MMP13MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6110964-A | FOR TREATING ARTHRITIS, INFLAMMATORY BOWEL DISEASE, CROHN'S DISEASE, EMPHYSEMA, ACUTE RESPIRATORY DISTRESS SYNDROME, ASTHMA CHRONIC OBSTRUCTIVE PULMONARY DISEASE, ALZHEIMER'S DISEASE, ORGAN TRANSPLANT TOXICITY, CACHEXIA, CANCER | PFIZER INC. (US) | 2000-08-29 | — | — | US | disclosed |