Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 2/20 | 0.36 |
| ▸ | MMP13 | P45452 | 2/20 | 0.36 |
| ▸ | RORC | P51449 | 4/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | TAS2R14 | Q9NYV8 | 4/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 3/20 | 0.32 |
| ▸ | MMP8 | P22894 | 2/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | MMP12 | P39900 | 1/20 | 0.32 |
| ▸ | MMP14 | P50281 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8077751 | 0.71 | MMP3 (0.43) | MMP1MMP13HDAC3HDAC1HDAC2 | |
| SCHEMBL7991333 | 0.64 | MMP2 (0.40) | MMP1MMP13MMP3MMP8MMP2 | |
| SCHEMBL7002033 | 0.62 | MMP1 (0.55) | MMP1MMP13MMP3MMP8MMP2 | |
| SCHEMBL7143052 | 0.62 | MMP13 (0.45) | MMP1MMP13MMP3MMP8MMP2 | |
| SCHEMBL7144631 | 0.61 | MMP13 (0.44) | MMP1MMP13RORCMMP3MMP8 | |
| SCHEMBL12570643 | 0.58 | PTGS2 (0.58) | MAPTPTGS2 | |
| SCHEMBL8652784 | 0.57 | PTGS1 (0.59) | MAPTPTGS2 | |
| SCHEMBL8652749 | 0.57 | PTGS2 (0.59) | PTGS2 | |
| SCHEMBL2636523 | 0.57 | MAPT (0.70) | MAPT | |
| SCHEMBL10203496 | 0.57 | MMP2 (0.63) | HSD11B1MMP2MMP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1070069-B1 | BICYCLIC HYDROXAMIC ACID DERIVATIVES | PFIZER PROD INC (US) | 2003-07-16 | — | — | EP | disclosed |