Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 7/20 | 0.40 |
| ▸ | MMP9 | P14780 | 7/20 | 0.40 |
| ▸ | MMP14 | P50281 | 5/20 | 0.40 |
| ▸ | MMP1 | P03956 | 14/20 | 0.40 |
| ▸ | MMP13 | P45452 | 12/20 | 0.40 |
| ▸ | MMP3 | P08254 | 5/20 | 0.40 |
| ▸ | MMP8 | P22894 | 5/20 | 0.40 |
| ▸ | MMP7 | P09237 | 2/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
| ▸ | MMP10 | P09238 | 1/20 | 0.40 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.40 |
| ▸ | MMP12 | P39900 | 1/20 | 0.35 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8072826 | 0.93 | MMP2 (0.44) | MMP2MMP9MMP14MMP1MMP13 | |
| SCHEMBL7993343 | 0.82 | ALDH1A1 (0.33) | MMP2MMP9MMP1MMP13MMP3 | |
| SCHEMBL7002033 | 0.80 | MMP1 (0.55) | MMP2MMP9MMP14MMP1MMP13 | |
| SCHEMBL25908 | 0.80 | MMP1 (0.56) | MMP2MMP9MMP14MMP1MMP13 | |
| SCHEMBL4575861 | 0.75 | MMP1 (0.42) | MMP2MMP9MMP14MMP1MMP13 | |
| SCHEMBL8077751 | 0.72 | MMP3 (0.43) | MMP2MMP9MMP14MMP1MMP13 | |
| SCHEMBL7000007 | 0.71 | MMP13 (0.66) | MMP2MMP9MMP14MMP1MMP13 | |
| SCHEMBL7001935 | 0.71 | MMP1 (0.46) | MMP2MMP9MMP14MMP1MMP13 | |
| SCHEMBL25832 | 0.71 | MMP1 (0.57) | MMP2MMP9MMP14MMP1MMP13 | |
| SCHEMBL6998203 | 0.69 | MMP1 (0.50) | MMP2MMP9MMP14MMP1MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288246-B1 | REACTION OF HYDROXYLAMINE WITH ALKYLSILYL HALIDE, HYDROLYSIS WITH ACID | PFIZER INC | 2001-09-11 | — | — | US | disclosed |
| EP-0949244-A2 | Process for preparing hydroxamic acids | Pfizer Products Inc. (US) | 1999-10-13 | — | — | EP | disclosed |