Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | TYK2 | P29597 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 6/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL808210 | 0.83 | PTPN11 (0.34) | PTPN11 | |
| SCHEMBL794037 | 0.82 | JAK2 (0.34) | JAK2JAK1TYK2JAK3 | |
| SCHEMBL808187 | 0.81 | HTR3E (0.43) | PTPN11 | |
| SCHEMBL808215 | 0.73 | DRD2 (0.36) | — | |
| Ammonia Solution, Strong SCHEMBL27935209 | 0.69 | SCD (0.32) | — | |
| SCHEMBL9996944 | 0.67 | L3MBTL1 (0.44) | JAK2JAK1TYK2JAK3 | |
| SCHEMBL795137 | 0.66 | CNR2 (0.33) | PTPN11 | |
| SCHEMBL15228263 | 0.64 | HTR3A (0.54) | — | |
| SCHEMBL9996994 | 0.63 | SMN1; SMN2 (0.48) | — | |
| SCHEMBL21815418 | 0.63 | HTR3E (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012035011-A1 | PESTICIDAL ARYLPYRROLIDINES | BAYER CROPSCIENCE AG (DE) | 2012-03-22 | — | — | WO | disclosed |