Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100A4 | P26447 | 1/20 | 0.44 |
| ▸ | PTPRC | P08575 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.37 |
| ▸ | BCL2 | P10415 | 2/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | AHR | P35869 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | METAP1 | P53582 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TDP2 | O95551 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29997437 | 0.69 | S100A4 (0.68) | S100A4PTPRCCYP2A6BCL2MCL1 | |
| SCHEMBL2147127 | 0.67 | TSHR (0.41) | S100A4PTPRCCA1CA2CA9 | |
| SCHEMBL3974835 | 0.66 | TGM2 (0.44) | S100A4CA1CA2CA4CA7 | |
| SCHEMBL340048 | 0.65 | ALOX15 (0.57) | S100A4PTPRCCYP2A6BCL2MCL1 | |
| SCHEMBL31016540 | 0.65 | S100A4 (0.62) | S100A4PTPRCCYP2A6BCL2MCL1 | |
| SCHEMBL2187975 | 0.65 | S100A4 (0.62) | S100A4PTPRCCYP2A6BCL2MCL1 | |
| SCHEMBL29502821 | 0.65 | ALOX15 (0.57) | S100A4PTPRCCYP2A6BCL2MCL1 | |
| Water SCHEMBL28487363 | 0.65 | ALOX15 (0.50) | S100A4PTPRCCYP2A6BCL2MCL1 | |
| SCHEMBL7605853 | 0.63 | PDK2 (0.48) | S100A4PTPRCCYP2A6BCL2MCL1 | |
| SCHEMBL7866191 | 0.63 | PTPRC (0.70) | S100A4PTPRCCYP2A6BCL2MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114556-A | Metallocene compound and its use as catalyst component | TARGOR GMBH (DE) | 2000-09-05 | — | — | US | disclosed |
| US-5962359-A | Metallocene compound and its use as catalyst component | TARGOR GMBH (DE) | 1999-10-05 | — | — | US | disclosed |
| EP-0723971-A2 | Metallocenes and their use as catalyst component | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-07-31 | — | — | EP | disclosed |