SCHEMBL340048

SCHEMBL340048

Oc1cc(Br)ccc1-c1ccc(Br)cc1O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 4/20 0.57
BCL2 P10415 2/20 0.56
MCL1 Q07820 2/20 0.56
CES2 O00748 1/20 0.48
GALR3 O60755 1/20 0.48
CYP1A2 P05177 1/20 0.48
CYP2C9 P11712 1/20 0.48
HPGD P15428 1/20 0.48
CASP1 P29466 1/20 0.48
CYP2C19 P33261 1/20 0.48
S100A4 P26447 1/20 0.48
ERN1 O75460 1/20 0.46
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CA4 P22748 1/20 0.44
CA7 P43166 1/20 0.44
CA9 Q16790 1/20 0.44
ESR1 P03372 1/20 0.42
ESR2 Q92731 1/20 0.42
IDO1 P14902 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29502821 1.00 ALOX15 (0.57) ALOX15BCL2MCL1CES2GALR3
SCHEMBL27164738 0.85 BCL2 (0.45) ALOX15BCL2MCL1CES2GALR3
SCHEMBL69661 0.81
SCHEMBL30007821 0.81
SCHEMBL5951047 0.80 ALOX5 (0.61) ALOX15BCL2MCL1HPGDESR2
SCHEMBL25434457 0.79 ALOX15 (0.62) ALOX15BCL2MCL1CES2GALR3
SCHEMBL582238 0.79
SCHEMBL27991140 0.79 ALOX15 (0.62) ALOX15BCL2MCL1CES2GALR3
SCHEMBL8743338 0.79 ALOX15 (0.62) ALOX15BCL2MCL1CES2GALR3
SCHEMBL31716139 0.78 CA9 (0.48) ALOX15BCL2MCL1CES2GALR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2539310-A1 SYNTHESIS OF MAGNOLOL AND ITS ANALOGUE COMPOUNDS Colgate-Palmolive Company (US) 2013-01-02 EP claimed
WO-2011106003-A1 SYNTHESIS OF MAGNOLOL AND ITS ANALOGUE COMPOUNDS COLGATE-PALMOLIVE COMPANY (US) 2011-09-01 WO claimed
EP-2271651-B1 ISOTHERMAL PROCESS FOR PHOSPHOROMONOCHLORIDITE SYNTHESIS DOW GLOBAL TECHNOLOGIES LLC (US) 2014-01-01 EP disclosed
EP-2346887-B1 SLURRY PROCESS FOR SYNTHESIS OF BISPHOSPHITES DOW TECHNOLOGY INVESTMENTS LLC (US) 2013-12-25 EP disclosed
US-8546600-B2 Slurry process for synthesis of bisphosphites and situ use thereof for producing bisphosphite DOW TECHNOLOGY INVESTMENTS LLC 2013-10-01 US disclosed
EP-2257560-B1 SLURRY PROCESS FOR PHOSPHOROMONOCHLORIDITE SYNTHESIS UNION CARBIDE CHEM PLASTIC (US) 2013-07-17 EP disclosed
US-8471066-B2 Slurry process for phosphoromonochloridite synthesis UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY LLC 2013-06-25 US disclosed
US-8097749-B2 Isothermal process for phosphoromonochloridite synthesis Union Carbide Chemical and Plastics Technology Technology 2012-01-17 US disclosed
US-20110196166-A1 SLURRY PROCESS FOR SYNTHESIS OF BISPHOSPHITES AND SITU USE THEREOF FOR PRODUCING BISPHOSPHITE DOW TECHNOLOGY INVESTMENTS LLC 2011-08-11 US disclosed
EP-2346887-A1 SLURRY PROCESS FOR SYNTHESIS OF BISPHOSPHITES Dow Technology Investments LLC (US) 2011-07-27 EP disclosed
US-20110021840-A1 SLURRY PROCESS FOR PHOSPHOROMONOCHLORIDITE SYTHESIS UNION CARBIDE CORPORATION 2011-01-27 US disclosed
EP-2257560-A1 SLURRY PROCESS FOR PHOSPHOROMONOCHLORIDITE SYNTHESIS Union Carbide Chemicals & Plastics Technology Llc (Formerly Union Carbide Chemicals & Plastics Technology Corporation) (US) 2010-12-08 EP disclosed
WO-2010042313-A1 SLURRY PROCESS FOR SYNTHESIS OF BISPHOSPHITES DOW TECHNOLOGY INVESTMENTS LLC (US) 2010-04-15 WO disclosed
US-20090247790-A1 ISOTHERMAL PROCESS FOR PHOSPHOROMONOCHLORIDITE SYNTHESIS UNION CARBIDE CORPORATION 2009-10-01 US disclosed
WO-2009120529-A1 SLURRY PROCESS FOR PHOSPHOROMONOCHLORIDITE SYNTHESIS UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY LLC (FORMERLY UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION) (US) 2009-10-01 WO disclosed
WO-2009120210-A1 ISOTHERMAL PROCESS FOR PHOSPHOROMONOCHLORIDITE SYNTHESIS DOW GLOBAL TECHNOLOGIES INC. (US) 2009-10-01 WO disclosed
US-7285616-B2 Aromatic polymer, method for producing the same and uses thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-10-23 US disclosed
US-20030180596-A1 Aromatic polymer, method for producing the same and uses thereof SUMITOMO CHEMICAL COMPANY, LIMITED 2003-09-25 US disclosed
EP-0590613-B1 Improved hydroformylation process UNION CARBIDE CHEM PLASTIC (US) 1997-01-08 EP disclosed
EP-0590613-A2 Improved hydroformylation process UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1994-04-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090247790-A1 ISOTHERMAL PROCESS FOR PHOSPHOROMONOCHLORIDITE SYNTHESIS PIM3, PLCB3, PLCD1 ALOX15 2223/4885BCL2 4000/4885MCL1 1716/4885
US-20110196166-A1 SLURRY PROCESS FOR SYNTHESIS OF BISPHOSPHITES AND SITU USE THEREOF FOR PRODUCING BISPHOSPHITE SOST, PLCB3, PPIP5K2 ALOX15 2202/4885BCL2 3431/4885MCL1 1140/4885
US-20110021840-A1 SLURRY PROCESS FOR PHOSPHOROMONOCHLORIDITE SYTHESIS PSPH, SPIN3, SYNGR2 ALOX15 3604/4885BCL2 2232/4885MCL1 1030/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.