Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL808229 | 0.77 | SIGMAR1 (0.32) | SIGMAR1 | |
| SCHEMBL808347 | 0.76 | HCRTR1 (0.34) | — | |
| SCHEMBL808333 | 0.76 | NPC1 (0.37) | SIGMAR1POLB | |
| SCHEMBL807994 | 0.75 | SIGMAR1 (0.31) | SIGMAR1 | |
| SCHEMBL807956 | 0.75 | PRCP (0.35) | — | |
| SCHEMBL808024 | 0.75 | TSHR (0.37) | SIGMAR1 | |
| SCHEMBL808221 | 0.75 | SIGMAR1 (0.32) | SIGMAR1POLBRECQL | |
| SCHEMBL807906 | 0.74 | SMN1; SMN2 (0.40) | — | |
| SCHEMBL10287187 | 0.74 | ALDH1A1 (0.45) | — | |
| SCHEMBL808224 | 0.74 | SIGMAR1 (0.32) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012035023-A1 | TRIAZINE-OXADIAZOLES | NOVARTIS AG (CH) | 2012-03-22 | — | — | WO | disclosed |