Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 4/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.32 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.32 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.32 |
| ▸ | TUBB | P07437 | 2/20 | 0.32 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.32 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.32 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.32 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.32 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.32 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.32 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.32 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.32 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.32 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.32 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.32 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.32 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL808048 | 0.87 | LMNA (0.36) | PRCPCHRM4TUBB4ATUBBTUBA3C | |
| SCHEMBL807935 | 0.86 | SMN1; SMN2 (0.41) | CHRM4TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL10286916 | 0.86 | ALDH1A1 (0.38) | PRCPCHRM4EPHX2GABRA1GABRA3 | |
| SCHEMBL808223 | 0.85 | LMNA (0.43) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL10286918 | 0.84 | GAA (0.39) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL10286920 | 0.81 | SMN1; SMN2 (0.41) | SMOMEN1GAAMAPTKMT2A | |
| SCHEMBL808022 | 0.80 | LMNA (0.35) | MEN1ALDH1A1GAAMAPTCYP2C9 | |
| SCHEMBL808032 | 0.78 | DHFR (0.34) | SLC18A3 | |
| SCHEMBL807920 | 0.75 | SIGMAR1 (0.33) | — | |
| SCHEMBL808024 | 0.74 | TSHR (0.37) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012035023-A1 | TRIAZINE-OXADIAZOLES | NOVARTIS AG (CH) | 2012-03-22 | — | — | WO | disclosed |