Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL808032 | 0.88 | DHFR (0.34) | SIGMAR1 | |
| SCHEMBL808343 | 0.87 | SCD (0.34) | SIGMAR1 | |
| SCHEMBL808232 | 0.85 | CNR2 (0.32) | SIGMAR1 | |
| SCHEMBL808046 | 0.82 | GAA (0.31) | — | |
| SCHEMBL808026 | 0.77 | — | — | |
| SCHEMBL808333 | 0.75 | NPC1 (0.37) | SIGMAR1SMN1; SMN2RAB9A | |
| SCHEMBL807920 | 0.75 | SIGMAR1 (0.33) | SIGMAR1 | |
| SCHEMBL807956 | 0.74 | PRCP (0.35) | MAPT | |
| SCHEMBL808229 | 0.74 | SIGMAR1 (0.32) | SIGMAR1 | |
| SCHEMBL808221 | 0.74 | SIGMAR1 (0.32) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012035023-A1 | TRIAZINE-OXADIAZOLES | NOVARTIS AG (CH) | 2012-03-22 | — | — | WO | disclosed |