Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.38 |
| ▸ | BTK | Q06187 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.37 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL807781 | 0.93 | ALDH1A1 (0.40) | ALDH1A1CYP3A4SMN1; SMN2USP2MAPT | |
| SCHEMBL808315 | 0.86 | SMN1; SMN2 (0.39) | MEN1KMT2AKCNH2HTTLMNA | |
| SCHEMBL808319 | 0.80 | NPC1 (0.43) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10287136 | 0.71 | ALDH1A1 (0.41) | MEN1KMT2AALDH1A1HTTHSD17B10 | |
| SCHEMBL15477324 | 0.69 | MAPK1 (0.49) | MEN1KMT2ABTKALDH1A1NTRK1 | |
| SCHEMBL20237020 | 0.67 | SMN1; SMN2 (0.68) | MEN1KMT2AALDH1A1CYP3A4NPC1 | |
| SCHEMBL807957 | 0.64 | LMNA (0.41) | MEN1KMT2AKCNH2ALDH1A1HTT | |
| SCHEMBL10287533 | 0.62 | ADRA2A (0.33) | ALDH1A1 | |
| SCHEMBL6992760 | 0.61 | ALDH1A1 (0.64) | ALDH1A1HTTEPHX2LMNANPC1 | |
| SCHEMBL10287195 | 0.59 | MTOR (0.42) | MEN1KMT2AKCNH2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012035023-A1 | TRIAZINE-OXADIAZOLES | NOVARTIS AG (CH) | 2012-03-22 | — | — | WO | disclosed |