Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 5/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | CXCR6 | O00574 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL808315 | 0.86 | SMN1; SMN2 (0.39) | NPC1RAB9ASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL807781 | 0.83 | ALDH1A1 (0.40) | SMN1; SMN2USP2CYP2D6 | |
| SCHEMBL807944 | 0.80 | MEN1 (0.38) | NPC1RAB9ASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL10287136 | 0.71 | ALDH1A1 (0.41) | NPC1RAB9ASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL796061 | 0.69 | GRM5 (0.43) | NPC1RAB9ASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL796014 | 0.67 | NPC1 (0.44) | NPC1RAB9ASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL2752741 | 0.64 | RAB9A (0.97) | NPC1RAB9ASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL807957 | 0.62 | LMNA (0.41) | NPC1RAB9ASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL10287533 | 0.62 | ADRA2A (0.33) | — | |
| SCHEMBL10287195 | 0.61 | MTOR (0.42) | NPC1RAB9ASMN1; SMN2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012035023-A1 | TRIAZINE-OXADIAZOLES | NOVARTIS AG (CH) | 2012-03-22 | — | — | WO | disclosed |