Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.33 |
| ▸ | TMPRSS15 | P98073 | 2/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.32 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.32 |
| ▸ | TPH1 | P17752 | 2/20 | 0.32 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.31 |
| ▸ | SRC | P12931 | 2/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ZAP70 | P43403 | 2/20 | 0.31 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.30 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.30 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.30 |
| ▸ | LDHA | P00338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1537414 | 0.78 | SLC7A5 (0.50) | PTGS2PTPN1ITGB3ITGA2BTPH1 | |
| SCHEMBL16972711 | 0.78 | SLC7A5 (0.50) | PTGS2PTPN1ITGB3ITGA2BTPH1 | |
| Tyrosine SCHEMBL8079541 | 0.78 | SLC7A5 (0.53) | PTGS2PTPN1TPH1SLC7A5ALOX15 | |
| Glutamic Acid SCHEMBL1931271 | 0.77 | THRB (0.35) | ITGB3ITGA2B | |
| Glutamic Acid SCHEMBL6141119 | 0.77 | THRB (0.36) | ITGB3ITGA2B | |
| Glutamine SCHEMBL8971920 | 0.77 | PTPN1 (0.33) | PTGS2PRSS1TMPRSS15PTPN1ITGB3 | |
| Lysine SCHEMBL4610451 | 0.75 | ITGB3 (0.52) | PTGS2PTPN1ITGB3ITGA2BTPH1 | |
| Lysine SCHEMBL5358311 | 0.75 | ITGB3 (0.52) | PTGS2PTPN1ITGB3ITGA2BTPH1 | |
| Tyrosine SCHEMBL8392469 | 0.74 | SLC7A5 (0.60) | PTGS2PTPN1ITGB3ITGA2BTPH1 | |
| SCHEMBL8588120 | 0.72 | PTPN1 (0.34) | PTGS2PRSS1TMPRSS15PTPN1ITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0668772-B1 | SPECIFIC IMMUNE SYSTEM MODULATION | UNIV YALE (US) | 2000-08-30 | — | — | EP | disclosed |