Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.34 |
| ▸ | SMO | Q99835 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PRCP | P42785 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | CCR5 | P51681 | 2/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10287788 | 0.92 | LMNA (0.38) | LMNAHTTNPC1RAB9ASMYD3 | |
| SCHEMBL10287790 | 0.86 | LMNA (0.38) | LMNAHTTNPC1RAB9ASMO | |
| SCHEMBL807957 | 0.86 | LMNA (0.41) | LMNAHTTNPC1RAB9ASMYD3 | |
| SCHEMBL10286916 | 0.77 | ALDH1A1 (0.38) | LMNAHTTNPC1RAB9ASMO | |
| SCHEMBL808223 | 0.75 | LMNA (0.43) | LMNAHTTNPC1RAB9ASMO | |
| SCHEMBL808048 | 0.73 | LMNA (0.36) | LMNAHTTNPC1RAB9ASMO | |
| SCHEMBL10286918 | 0.72 | GAA (0.39) | LMNAHTTNPC1RAB9ASMO | |
| SCHEMBL797212 | 0.71 | LMNA (0.43) | LMNAHTTNPC1RAB9ASMO | |
| SCHEMBL807956 | 0.69 | PRCP (0.35) | SMOGAAPRCPEPHX2KCNH2 | |
| SCHEMBL808022 | 0.69 | LMNA (0.35) | LMNAHTTNPC1RAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012035023-A1 | TRIAZINE-OXADIAZOLES | NOVARTIS AG (CH) | 2012-03-22 | — | — | WO | disclosed |