Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.35 |
| ▸ | TSHR | P16473 | 4/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL808034 | 0.88 | GAA (0.35) | LMNATSHRNPSR1GAASMN1; SMN2 | |
| SCHEMBL808223 | 0.88 | LMNA (0.43) | LMNATSHRNPSR1GAASMN1; SMN2 | |
| SCHEMBL808048 | 0.85 | LMNA (0.36) | LMNATSHRGAASMN1; SMN2HTT | |
| SCHEMBL10286916 | 0.84 | ALDH1A1 (0.38) | LMNATSHRNPSR1GAASMN1; SMN2 | |
| SCHEMBL10286918 | 0.84 | GAA (0.39) | LMNATSHRNPSR1GAASMN1; SMN2 | |
| SCHEMBL808046 | 0.83 | GAA (0.31) | GAA | |
| SCHEMBL10286917 | 0.82 | GRM5 (0.41) | LMNATSHRNPSR1GAASMN1; SMN2 | |
| SCHEMBL807956 | 0.80 | PRCP (0.35) | GAAALDH1A1MAPTMEN1CYP2C9 | |
| SCHEMBL807935 | 0.79 | SMN1; SMN2 (0.41) | LMNATSHRGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL10287144 | 0.73 | CPT2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012035023-A1 | TRIAZINE-OXADIAZOLES | NOVARTIS AG (CH) | 2012-03-22 | — | — | WO | disclosed |