Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCL8 | P10145 | 2/20 | 0.58 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | RXRA | P19793 | 1/20 | 0.48 |
| ▸ | RXRB | P28702 | 1/20 | 0.48 |
| ▸ | RXRG | P48443 | 1/20 | 0.48 |
| ▸ | VNN1 | O95497 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.46 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CAMK2A | Q9UQM7 | 2/20 | 0.44 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29782307 | 1.00 | CXCL8 (0.58) | CXCL8AKR1B1CHRM1RXRARXRB | |
| Hydrochloric Acid SCHEMBL2530814 | 0.98 | CXCL8 (0.57) | CXCL8AKR1B1CHRM1RXRARXRB | |
| SCHEMBL29718710 | 0.87 | CXCL8 (0.49) | CXCL8AKR1B1CHRM1RXRARXRB | |
| SCHEMBL6963700 | 0.86 | VNN1 (0.47) | CXCL8RXRARXRBRXRGVNN1 | |
| SCHEMBL31736338 | 0.85 | CXCL8 (0.46) | CXCL8AKR1B1CHRM1RXRARXRB | |
| SCHEMBL8088589 | 0.85 | CXCL8 (0.54) | CXCL8AKR1B1CHRM1VNN1L3MBTL1 | |
| SCHEMBL6195827 | 0.84 | L3MBTL1 (0.57) | CXCL8RXRARXRBRXRGVNN1 | |
| SCHEMBL10565876 | 0.84 | GRIN2B (0.48) | CXCL8RXRARXRBRXRGVNN1 | |
| SCHEMBL2530811 | 0.84 | VNN1 (0.46) | CXCL8RXRARXRBRXRGVNN1 | |
| SCHEMBL14661063 | 0.83 | P2RX7 (0.50) | CXCL8AKR1B1CHRM1RXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 227 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250346778-A1 | FLUORINE-CONTAINING COMPOUND | DAIKIN INDUSTRIES, LTD. (JP) | 2025-11-13 | — | — | US | disclosed |
| EP-4079724-B1 | 2-(2-CHLOROPHENYL)-N-(5-SULFAMOYLISOQUINOLIN-7-YL)ACETAMIDE DERIVATIVES AND SIMILAR COMPOUNDS AS P2X4 ANTAGONISTS FOR THE TREATMENT OF E.G. URINARY TRACT DISEASES | WUHAN LL SCIENCE & TECHNOLOGY DEVELOPMENT CO LTD (CN) | 2025-11-12 | — | — | EP | disclosed |
| US-20250340752-A1 | FLUORINATED POLYMER | DAIKIN INDUSTRIES, LTD. (JP) | 2025-11-06 | — | — | US | disclosed |
| US-20250333902-A1 | FLUORINE-CONTAINING COMPOUND | DAIKIN INDUSTRIES, LTD. (JP) | 2025-10-30 | — | — | US | disclosed |
| EP-4574872-A1 | FLUORINE-CONTAINING COMPOUND | DAIKIN INDUSTRIES, LTD. (JP) | 2025-06-25 | — | — | EP | disclosed |
| EP-4538304-A1 | FLUORINATED POLYMER | DAIKIN INDUSTRIES, LTD. (JP) | 2025-04-16 | — | — | EP | disclosed |
| EP-4516773-A1 | FLUORINE-CONTAINING COMPOUND | DAIKIN INDUSTRIES, LTD. (JP) | 2025-03-05 | — | — | EP | disclosed |
| CN-118239953-A | Compounds for the treatment of PI3K gamma mediated diseases and uses thereof | 中国科学院合肥物质科学研究院 | 2024-06-25 | — | — | CN | disclosed |
| CN-115054600-B | Aromatic sulfonamide derivatives | 拜耳制药股份公司 | 2024-06-14 | — | — | CN | disclosed |
| WO-2024067560-A1 | SULFONAMIDE COMPOUND AND MEDICAL USE THEREOF | 中国药科大学 | 2024-04-04 | — | — | WO | disclosed |
| EP-1851204-A1 | NAPHTHALENE DERIVATIVES AS MODULATORS OF THE GLUCOCORTICOID RECEPTOR | SmithKline Beecham Corporation (US) | 2007-11-07 | — | — | EP | disclosed |
| WO-2007067575-A2 | PROCESS FOR PREPARING SUBSTITUTED ARYL CYCLOALKANOL DERIVATIVES | WYETH (US) | 2007-06-14 | — | — | WO | disclosed |
| US-20070129377-A1 | Process for Preparing Substituted Aryl Cycloalkanol Derivatives | WYETH (US) | 2007-06-07 | — | — | US | disclosed |
| WO-2006091592-A1 | NAPHTHALENE DERIVATIVES AS MODULATORS OF THE GLUCOCORTICOID RECEPTOR | SMITHKLINE BEECHAM CORPORATION (US) | 2006-08-31 | — | — | WO | disclosed |
| US-20060106035-A1 | Phenyl-substituted pyrazolopyrimidines | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2006-05-18 | — | — | US | disclosed |
| US-20050026929-A1 | Novel phenyl derivatives as inducers of apoptosis | AXYS PHARMACEUTICALS, INC. (US) | 2005-02-03 | — | — | US | disclosed |
| CN-1575191-A | Treatment of insulin resistance syndrome and type 2 diabetes with PDE9 inhibitors | PFIZER PROD INC (US) | 2005-02-02 | — | — | CN | disclosed |
| WO-2003090680-A2 | NOVEL PHENYL DERIVATIVES AS INDUCERS OF APOPTOSIS | AXYS PHARMACEUTICALS, INC. (US) | 2003-11-06 | — | — | WO | disclosed |
| US-6090805-A | Tocolytic oxytocin receptor antagonists | MERCK & CO., INC. (US) | 2000-07-18 | — | — | US | disclosed |
| US-5968938-A | Piperazine oxytocin receptor antagonists | MERCK & CO., INC. (US) | 1999-10-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070129377-A1 | Process for Preparing Substituted Aryl Cycloalkanol Derivatives | CYP1A2, CYP3A7, CYP3A43 | CXCL8 3980/4885AKR1B1 368/4885CHRM1 2844/4885 |
| US-20050026929-A1 | Novel phenyl derivatives as inducers of apoptosis | BAX, BAD, CASP3 | CXCL8 3512/4885AKR1B1 1510/4885CHRM1 4787/4885 |
| US-20060106035-A1 | Phenyl-substituted pyrazolopyrimidines | P2RX4, P2RY4, P2RX5 | CXCL8 1473/4885AKR1B1 3329/4885CHRM1 617/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.