Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | C1R | P00736 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | CTSG | P08311 | 1/20 | 0.35 |
| ▸ | CMA1 | P23946 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | PTGES | O14684 | 2/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8079566 | 0.93 | LMNA (0.37) | LMNATP53SMN1; SMN2C1RPRSS1 | |
| SCHEMBL9407932 | 0.90 | LMNA (0.35) | LMNATP53SMN1; SMN2C1RPRSS1 | |
| SCHEMBL8469903 | 0.88 | LMNA (0.40) | LMNATP53C1RPRSS1ALDH1A1 | |
| SCHEMBL8074295 | 0.88 | MAPT (0.40) | LMNATP53SMN1; SMN2C1RPRSS1 | |
| Bromide SCHEMBL9408007 | 0.85 | KEAP1 (0.41) | LMNATP53SMN1; SMN2C1RPRSS1 | |
| SCHEMBL8074300 | 0.85 | ALDH1A1 (0.40) | LMNATP53SMN1; SMN2C1RALDH1A1 | |
| SCHEMBL8080887 | 0.84 | LMNA (0.44) | LMNATP53SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL8079548 | 0.83 | ALDH1A1 (0.38) | LMNATP53SMN1; SMN2C1RALDH1A1 | |
| SCHEMBL9407935 | 0.82 | GAA (0.36) | LMNASMN1; SMN2ALDH1A1CTSGCMA1 | |
| SCHEMBL8469910 | 0.81 | LMNA (0.38) | LMNATP53C1RPRSS1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0330050-B1 | Special chemiluminescent acridine derivatives and their use in luminescence immunoassays | DADE BEHRING MARBURG GMBH (DE) | 2000-08-23 | — | — | EP | disclosed |
| EP-0602524-A1 | Chemiluminescence marked sequences and their use in sequence testing | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-06-22 | — | — | EP | disclosed |
| EP-0330050-A2 | Special chemiluminescent acridine derivatives and their use in luminescence immunoassays | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-08-30 | — | — | EP | disclosed |