Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 3/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | BMP1 | P13497 | 1/20 | 0.36 |
| ▸ | C1R | P00736 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8074300 | 0.95 | ALDH1A1 (0.40) | ALDH1A1LMNATSHRHSD17B10KMT2A | |
| SCHEMBL8470438 | 0.90 | ALDH1A1 (0.42) | ALDH1A1LMNATSHRMMP3HSD17B10 | |
| SCHEMBL8079566 | 0.87 | LMNA (0.37) | ALDH1A1LMNAGAAMAPTHPGD | |
| Bromide SCHEMBL8076287 | 0.86 | KEAP1 (0.43) | ALDH1A1LMNATSHRMMP3KMT2A | |
| SCHEMBL8076560 | 0.86 | MMP3 (0.42) | ALDH1A1LMNATSHRMMP3KMT2A | |
| SCHEMBL9407899 | 0.84 | ALDH1A1 (0.43) | ALDH1A1LMNATSHRKMT2AGAA | |
| SCHEMBL9407932 | 0.84 | LMNA (0.35) | ALDH1A1LMNAGAAMAPTHPGD | |
| SCHEMBL8066342 | 0.84 | ALDH1A1 (0.38) | ALDH1A1LMNATSHRKMT2AGAA | |
| SCHEMBL8470105 | 0.84 | ALDH1A1 (0.43) | ALDH1A1LMNATSHRHSD17B10KMT2A | |
| SCHEMBL9407920 | 0.84 | CXCR3 (0.34) | LMNAMMP3MAPTHSP90AA1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0330050-B1 | Special chemiluminescent acridine derivatives and their use in luminescence immunoassays | DADE BEHRING MARBURG GMBH (DE) | 2000-08-23 | — | — | EP | disclosed |
| EP-0330050-A2 | Special chemiluminescent acridine derivatives and their use in luminescence immunoassays | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-08-30 | — | — | EP | disclosed |