Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.32 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.31 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.31 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.31 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 2/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8507588 | 0.87 | LOXL2 (0.37) | LOXL2MCL1ALOX5KDM4EALDH1A1 | |
| SCHEMBL8037995 | 0.84 | LOXL2 (0.40) | LOXL2MCL1ALOX5ALDH1A1MAOA | |
| SCHEMBL8038421 | 0.76 | LOXL2 (0.40) | LOXL2MCL1KDM4EALDH1A1GAA | |
| SCHEMBL2089679 | 0.76 | LOXL2 (0.40) | LOXL2MCL1KDM4EALDH1A1GAA | |
| SCHEMBL26244767 | 0.75 | ALDH1A1 (0.32) | KDM4EALDH1A1GAAHTTHPGD | |
| SCHEMBL23532166 | 0.74 | TTR (0.42) | PDCD1CD274ALOX5KDM4EALDH1A1 | |
| SCHEMBL27185500 | 0.73 | SIRT2 (0.42) | MCL1ALDH1A1MAOAMAOBMEN1 | |
| SCHEMBL21230524 | 0.72 | ALDH1A1 (0.37) | ALOX5KDM4EALDH1A1HTTMAOA | |
| SCHEMBL2256874 | 0.71 | KDM4E (0.46) | KDM4EALDH1A1SMN1; SMN2HTTMAOA | |
| SCHEMBL1855422 | 0.70 | GPR52 (0.53) | MAOBKMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6063810-A | ENANTIOMORPHS | SYNTHELABO (FR) | 2000-05-16 | — | — | US | disclosed |