Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CCKBR | P32239 | 1/20 | 0.33 |
| ▸ | LHCGR | P22888 | 1/20 | 0.33 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8089877 | 0.90 | ALDH1A1 (0.39) | ALDH1A1MEN1LMNAKMT2AHTT | |
| SCHEMBL8095731 | 0.73 | CCKBR (0.46) | ALDH1A1CCKBR | |
| SCHEMBL7597322 | 0.70 | CCKBR (0.58) | CCKBR | |
| SCHEMBL8089866 | 0.70 | CCKBR (0.41) | ALDH1A1HTTCCKBR | |
| SCHEMBL8785303 | 0.65 | ALDH1A1 (0.34) | ALDH1A1MEN1KMT2AHTTCCKBR | |
| SCHEMBL8093420 | 0.65 | CCKBR (0.45) | CCKBR | |
| SCHEMBL8089873 | 0.65 | CCKAR (0.55) | ALDH1A1CCKBR | |
| SCHEMBL8089854 | 0.59 | CASR (0.44) | ALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL8089856 | 0.59 | CASR (0.44) | ALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL6904260 | 0.58 | ACE (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6096885-A | EXHIBIT AGONIST ACTIVITY FOR CCK-A RECEPTORS THEREBY ENABLING THEM TO MODULATE THE HORMONES GASTRIN AND CHOLECYSTOKININ IN MAMMALS. | GLAXO WELLCOME INC. (US) | 2000-08-01 | — | — | US | disclosed |
| EP-0785944-A1 | ACYL AMINO ACETAMIDE DERIVATIVES WITH AGONIST ACTIVITY FOR CCK-A RECEPTORS | GLAXO WELLCOME INC. (US) | 1997-07-30 | — | — | EP | disclosed |
| WO-1996011940-A1 | ACYL AMINO ACETAMIDE DERIVATIVES WITH AGONIST ACTIVITY FOR CCK-A RECEPTORS | GLAXO WELLCOME INC. (US) | 1996-04-25 | — | — | WO | disclosed |