Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27531992 | 0.81 | PNMT (0.36) | ALDH1A1SMN1; SMN2MAPTHPGDL3MBTL1 | |
| SCHEMBL10351892 | 0.81 | MEN1 (0.41) | ALDH1A1SMN1; SMN2HPGDL3MBTL1NPC1 | |
| SCHEMBL3262579 | 0.79 | TRPA1 (0.41) | ALDH1A1SMN1; SMN2HPGDL3MBTL1FGFR1 | |
| SCHEMBL8083455 | 0.78 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL8088430 | 0.77 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL944379 | 0.76 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2MAPTHPGDTSHR | |
| SCHEMBL10351891 | 0.74 | MEN1 (0.48) | ALDH1A1SMN1; SMN2HPGDL3MBTL1MAPK1 | |
| SCHEMBL6057067 | 0.73 | MCHR1 (0.42) | ALDH1A1SMN1; SMN2MAPTHPGDL3MBTL1 | |
| SCHEMBL27233210 | 0.72 | L3MBTL1 (0.41) | ALDH1A1SMN1; SMN2HPGDL3MBTL1FGFR1 | |
| SCHEMBL8810167 | 0.72 | KMT2A (0.38) | ALDH1A1SMN1; SMN2MAPTHPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1044980-A1 | PROCESS FOR PRODUCING TOLUENE DERIVATIVES | Ihara Chemical Industry Co., Ltd. (JP) | 2000-10-18 | — | — | EP | disclosed |