Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8083579 | 0.94 | ALDH1A1 (0.46) | ALDH1A1MAPK1LMNAATMKMT2A | |
| SCHEMBL8091445 | 0.89 | ALDH1A1 (0.43) | ALDH1A1MAPK1LMNAATMKMT2A | |
| SCHEMBL8083627 | 0.85 | SMN1; SMN2 (0.44) | ALDH1A1LMNAKMT2AMEN1POLB | |
| SCHEMBL8095182 | 0.84 | MMP8 (0.40) | ATMTSHRL3MBTL1CYP1A2CYP2C9 | |
| SCHEMBL8091583 | 0.84 | MC4R (0.39) | — | |
| SCHEMBL8091668 | 0.84 | MMP8 (0.39) | ALDH1A1ATML3MBTL1 | |
| SCHEMBL8091452 | 0.83 | ALDH1A1 (0.43) | ALDH1A1MAPK1LMNAATMKMT2A | |
| SCHEMBL8090153 | 0.82 | MMP8 (0.40) | ALDH1A1ATMTSHRL3MBTL1CYP1A2 | |
| SCHEMBL8090157 | 0.79 | MTNR1A (0.41) | ALDH1A1LMNAPOLB | |
| SCHEMBL8091588 | 0.78 | MC4R (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792883-B1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2000-12-20 | — | — | EP | disclosed |
| EP-0792883-A1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1997-09-03 | — | — | EP | disclosed |