Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | IDE | P14735 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | METAP1 | P53582 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | RGS12 | O14924 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8089904 | 0.89 | LMNA (0.51) | SMN1; SMN2LMNAALDH1A1ACVR1MAPT | |
| SCHEMBL8084125 | 0.87 | TNKS (0.46) | SMN1; SMN2LMNAPOLBNPSR1MEN1 | |
| SCHEMBL8084112 | 0.86 | MAPT (0.48) | SMN1; SMN2LMNAPOLBALDH1A1MAPT | |
| SCHEMBL8084897 | 0.86 | LMNA (0.42) | SMN1; SMN2LMNAPOLBALDH1A1ACVR1 | |
| SCHEMBL8084115 | 0.86 | MEN1 (0.45) | SMN1; SMN2LMNAPOLBALDH1A1ACVR1 | |
| SCHEMBL8084900 | 0.86 | SMN1; SMN2 (0.46) | SMN1; SMN2LMNAALDH1A1MAPTNPSR1 | |
| SCHEMBL8084719 | 0.85 | ALOX15 (0.49) | SMN1; SMN2LMNAPOLBALDH1A1MAPT | |
| SCHEMBL8084656 | 0.84 | SMN1; SMN2 (0.39) | SMN1; SMN2LMNAPOLBALDH1A1MAPT | |
| SCHEMBL8084676 | 0.83 | CCNC (0.46) | SMN1; SMN2LMNAPOLBALDH1A1MAPT | |
| SCHEMBL8084675 | 0.83 | SMN1; SMN2 (0.44) | SMN1; SMN2LMNAALDH1A1MAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6057447-A | BACTERICIDES FOR CAMPYLOBACTER | ZENYAKU KOGYO KABUSHIKI KAISHA (JP) | 2000-05-02 | — | — | US | disclosed |
| EP-0926139-A1 | QUINOLINE SULFIDE DERIVATIVES | ZENYAKU KOGYO KABUSHIKIKAISHA (JP) | 1999-06-30 | — | — | EP | disclosed |