Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.40 |
| ▸ | HRH2 | P25021 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | METAP1 | P53582 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8089904 | 0.91 | LMNA (0.51) | LMNASMN1; SMN2ACVR1MAPTALDH1A1 | |
| SCHEMBL8084112 | 0.88 | MAPT (0.48) | LMNASMN1; SMN2MAPTALDH1A1HPGD | |
| SCHEMBL8084125 | 0.87 | TNKS (0.46) | LMNASMN1; SMN2HRH2HRH1NPSR1 | |
| SCHEMBL8084141 | 0.86 | SMN1; SMN2 (0.40) | LMNASMN1; SMN2ACVR1MAPTALDH1A1 | |
| SCHEMBL8084115 | 0.86 | MEN1 (0.45) | LMNASMN1; SMN2ACVR1MAPTALDH1A1 | |
| SCHEMBL8084900 | 0.86 | SMN1; SMN2 (0.46) | LMNASMN1; SMN2MAPTALDH1A1TSHR | |
| SCHEMBL8084676 | 0.85 | CCNC (0.46) | LMNASMN1; SMN2MAPTALDH1A1TSHR | |
| SCHEMBL8084719 | 0.85 | ALOX15 (0.49) | LMNASMN1; SMN2MAPTALDH1A1HPGD | |
| SCHEMBL8084819 | 0.84 | ALDH1A1 (0.43) | LMNASMN1; SMN2MAPTALDH1A1HPGD | |
| SCHEMBL8084656 | 0.84 | SMN1; SMN2 (0.39) | LMNASMN1; SMN2MAPTALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6057447-A | BACTERICIDES FOR CAMPYLOBACTER | ZENYAKU KOGYO KABUSHIKI KAISHA (JP) | 2000-05-02 | — | — | US | disclosed |
| EP-0926139-A1 | QUINOLINE SULFIDE DERIVATIVES | ZENYAKU KOGYO KABUSHIKIKAISHA (JP) | 1999-06-30 | — | — | EP | disclosed |