Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNC | P24863 | 1/20 | 0.46 |
| ▸ | CDK8 | P49336 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | GFER | P55789 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | NCF1 | P14598 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CASP6 | P55212 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8088254 | 0.90 | ADRA2A (0.51) | POLBNPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL8084112 | 0.89 | MAPT (0.48) | POLBMAPTALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL8076752 | 0.89 | MEN1 (0.42) | TSHRPOLBNPC1RAB9AMAPT | |
| SCHEMBL8089904 | 0.88 | LMNA (0.51) | TSHRMAPTALDH1A1GAAMAPK1 | |
| SCHEMBL8084826 | 0.88 | NPC1 (0.50) | TSHRPOLBNPC1RAB9AMAPT | |
| SCHEMBL8084820 | 0.88 | ALDH1A1 (0.47) | POLBNPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL8089852 | 0.87 | ALDH1A1 (0.46) | TSHRNPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL8084900 | 0.87 | SMN1; SMN2 (0.46) | TSHRNPC1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL8088222 | 0.87 | DRD2 (0.43) | POLBNPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL8076727 | 0.86 | MAPT (0.51) | POLBNPC1RAB9AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6057447-A | BACTERICIDES FOR CAMPYLOBACTER | ZENYAKU KOGYO KABUSHIKI KAISHA (JP) | 2000-05-02 | — | — | US | disclosed |
| EP-0926139-A1 | QUINOLINE SULFIDE DERIVATIVES | ZENYAKU KOGYO KABUSHIKIKAISHA (JP) | 1999-06-30 | — | — | EP | disclosed |