SCHEMBL8084235

SCHEMBL8084235

C=CS(=O)(=O)c1[c]cccc1

nearest known ligand 0.35

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.35
ALDH1A1 P00352 1/20 0.35
LMNA P02545 1/20 0.35
TP53 P04637 1/20 0.35
MAPT P10636 1/20 0.35
TSHR P16473 1/20 0.35
XBP1 P17861 1/20 0.35
MAPK1 P28482 1/20 0.35
HTT P42858 1/20 0.35
RAB9A P51151 1/20 0.35
MDM2 Q00987 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
HSD17B10 Q99714 1/20 0.35
TLR9 Q9NR96 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL219484 0.76 TSHR (0.42) ALDH1A1LMNATSHRSMN1; SMN2HSD17B10
SCHEMBL150811 0.75 HTR6 (0.38)
SCHEMBL1140103 0.75 ALDH1A1 (0.41) ALDH1A1LMNAMAPTHTT
SCHEMBL8387010 0.73 HTR6 (0.31)
SCHEMBL1464343 0.72 KDM4E (0.41) ALDH1A1LMNAMAPTTSHRMAPK1
SCHEMBL77668 0.71 PTGS2 (0.33)
SCHEMBL1727931 0.71 ELANE (0.38)
SCHEMBL76930 0.71 CA2 (0.42) LMNA
SCHEMBL1727551 0.71
SCHEMBL1726647 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0202570-B1 REACTIVE DYES BASF Aktiengesellschaft (DE) 1989-03-22 EP claimed
US-4798887-A Azo dyes of methylaniline disulfonic acid coupled with naphthylamine sulfonic acid BASF AKTIENGESELLSCHAFT (DE) 1989-01-17 US claimed
EP-0202570-A1 Reactive dyes BASF Aktiengesellschaft (DE) 1986-11-26 EP claimed
US-10190255-B2 Mixtures of fiber-reactive azo dyes, their preparation and their use DYSTAR COLOURS DISTRIBUTION GMBH (DE) 2019-01-29 US disclosed
US-10138596-B2 Mixtures of fiber-reactive azo dyes, their preparation and their use DYSTAR COLOURS DISTRIBUTION GMBH (DE) 2018-11-27 US disclosed
EP-2912119-B1 MIXTURES OF FIBER-REACTIVE AZO DYES, THEIR PREPARATION AND THEIR USE DYSTAR COLOURS DISTRIB GMBH (DE) 2016-12-14 EP disclosed
EP-2912118-B1 MIXTURES OF FIBER-REACTIVE AZO DYES, THEIR PREPARATION AND THEIR USE DYSTAR COLOURS DISTRIB GMBH (DE) 2016-09-07 EP disclosed
CN-102292400-B The disazo dyes of fibre-active copper complexing DYSTAR COLOURS DISTRIBUTION GMBH (DE) 2016-01-20 CN disclosed
US-20150284904-A1 MIXTURES OF FIBER-REACTIVE AZO DYES, THEIR PREPARATION AND THEIR USE DYSTAR COLOURS DISTRIBUTION GMBH (DE) 2015-10-08 US disclosed
US-20150267345-A1 MIXTURES OF FIBER-REACTIVE AZO DYES, THEIR PREPARATION AND THEIR USE DYSTAR COLOURS DISTRIBUTION GMBH (DE) 2015-09-24 US disclosed
CN-104937039-A Mixtures of fiber-reactive azo dyes, their preparation and their use DYSTAR COLOURS DISTRIB GMBH 2015-09-23 CN disclosed
EP-0962500-A1 Water soluble monoazo compounds, process for their preparation and their use as dyestuffs DyStar Textilfarben GmbH & Co., Textilfarben Deutschland KG (DE) 1999-12-08 EP disclosed
EP-0957137-A2 Mixture of water soluble reactive azo dyes, process to manufacture it and its use DyStar Textilfarben GmbH & Co. Deutschland KG (DE) 1999-11-17 EP disclosed
US-5980590-A HIGH COLOR YIELD; FOR DYEING OR PRINTING OF CELLULOSIC FIBERS, WOOL, AND POLYAMIDE FIBERS DYSTAR TEXILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 1999-11-09 US disclosed
EP-0486176-B1 Reactive dyes ZENECA LTD (GB) 1996-12-11 EP disclosed
EP-0202570-B1 REACTIVE DYES BASF Aktiengesellschaft (DE) 1989-03-22 EP disclosed
US-4798887-A Azo dyes of methylaniline disulfonic acid coupled with naphthylamine sulfonic acid BASF AKTIENGESELLSCHAFT (DE) 1989-01-17 US disclosed
US-4798887-A Azo dyes of methylaniline disulfonic acid coupled with naphthylamine sulfonic acid BASF AKTIENGESELLSCHAFT (DE) 1989-01-17 US disclosed
EP-0202570-A1 Reactive dyes BASF Aktiengesellschaft (DE) 1986-11-26 EP disclosed
EP-0202570-A1 Reactive dyes BASF Aktiengesellschaft (DE) 1986-11-26 EP disclosed