Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | DNMT1 | P26358 | 2/20 | 0.42 |
| ▸ | DNMT3A | Q9Y6K1 | 2/20 | 0.42 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | DNMT3L | Q9UJW3 | 1/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.40 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8088227 | 0.86 | DNMT1 (0.44) | MAPTALDH1A1LMNARAB9ADNMT1 | |
| SCHEMBL8088287 | 0.84 | CYP17A1 (0.46) | RAB9ANAMPTDNMT1DNMT3ACYP17A1 | |
| SCHEMBL8084739 | 0.80 | ALDH1A1 (0.60) | MAPTALDH1A1LMNARAB9AKMT2A | |
| SCHEMBL8088268 | 0.78 | HSD17B10 (0.50) | MAPTALDH1A1LMNARAB9AKMT2A | |
| SCHEMBL8084900 | 0.77 | SMN1; SMN2 (0.46) | MAPTALDH1A1LMNANAMPTKMT2A | |
| SCHEMBL8076734 | 0.77 | HDAC6 (0.47) | MAPTALDH1A1LMNARAB9ADNMT1 | |
| SCHEMBL8084102 | 0.76 | HTR2C (0.53) | MAPTALDH1A1LMNARAB9AKMT2A | |
| SCHEMBL8084757 | 0.76 | ALDH1A1 (0.49) | MAPTALDH1A1LMNARAB9AKMT2A | |
| SCHEMBL8084097 | 0.76 | HTR2C (0.48) | MAPTALDH1A1LMNARAB9AKMT2A | |
| SCHEMBL7082250 | 0.76 | NAMPT (0.51) | NAMPTDNMT1DNMT3ADNMT3LMAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6057447-A | BACTERICIDES FOR CAMPYLOBACTER | ZENYAKU KOGYO KABUSHIKI KAISHA (JP) | 2000-05-02 | — | — | US | disclosed |
| EP-0926139-A1 | QUINOLINE SULFIDE DERIVATIVES | ZENYAKU KOGYO KABUSHIKIKAISHA (JP) | 1999-06-30 | — | — | EP | disclosed |