SCHEMBL8084648

SCHEMBL8084648

C=CCc1ccc2c(F)c(O)ccc2c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
XDH P47989 1/20 0.56
GABRA1 P14867 8/20 0.54
GABRB2 P47870 8/20 0.54
ALDH1A1 P00352 3/20 0.54
CNR2 P34972 3/20 0.54
MAPT P10636 3/20 0.54
MEN1 O00255 2/20 0.54
GAA P10253 2/20 0.54
CNR1 P21554 2/20 0.54
KMT2A Q03164 2/20 0.54
PPARG P37231 2/20 0.54
PPARD Q03181 2/20 0.54
KDM4E B2RXH2 1/20 0.54
ALDH2 P05091 1/20 0.54
AKR1B1 P15121 1/20 0.54
HPGD P15428 1/20 0.54
NPSR1 Q6W5P4 1/20 0.54
ESR1 P03372 2/20 0.49
ESR2 Q92731 2/20 0.49
ALOX5 P09917 6/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29946571 0.78 ERN1 (0.59) XDHGABRA1GABRB2ALDH1A1CNR2
SCHEMBL15255826 0.77 XDH (0.55) XDHGABRA1GABRB2ALDH1A1CNR2
SCHEMBL10340887 0.75 XDH (0.68) XDHGABRA1GABRB2ALDH1A1CNR2
SCHEMBL3172565 0.75 CNR1 (0.53) CNR2MEN1GAACNR1KMT2A
SCHEMBL3259762 0.74 XDH (0.58) XDHGABRA1GABRB2ALDH1A1CNR2
Hydroxychavicol SCHEMBL43300 0.73 XDH (1.00) XDHGABRA1GABRB2ALDH1A1CNR2
Hydroxychavicol SCHEMBL15676540 0.73 XDH (1.00) XDHGABRA1GABRB2ALDH1A1CNR2
SCHEMBL16487290 0.73 ALDH1A1 (0.48) XDHGABRA1GABRB2ALDH1A1CNR2
SCHEMBL30083985 0.73 ALDH1A1 (0.48) XDHGABRA1GABRB2ALDH1A1CNR2
SCHEMBL7555913 0.72 XDH (0.56) XDHGABRA1GABRB2ALDH1A1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2000026342-A PHENYLETHYNYLNAPHTHALENE DERIVATIVE DAINIPPON INK & CHEM INC 2000-01-25 JP disclosed