Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | RAD52 | P43351 | 2/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8088254 | 0.87 | ADRA2A (0.51) | ALDH1A1SMN1; SMN2KDM4ENPSR1LMNA | |
| SCHEMBL8084676 | 0.85 | CCNC (0.46) | ALDH1A1SMN1; SMN2KDM4ENPSR1LMNA | |
| SCHEMBL8084820 | 0.85 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2KDM4ENPSR1LMNA | |
| SCHEMBL8084826 | 0.85 | NPC1 (0.50) | ALDH1A1SMN1; SMN2KDM4ENPSR1LMNA | |
| SCHEMBL8089852 | 0.85 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2KDM4ENPSR1LMNA | |
| SCHEMBL8084897 | 0.84 | LMNA (0.42) | ALDH1A1SMN1; SMN2KDM4ENPSR1LMNA | |
| SCHEMBL8076727 | 0.84 | MAPT (0.51) | ALDH1A1SMN1; SMN2NPSR1LMNAKMT2A | |
| SCHEMBL8088295 | 0.83 | MAPT (0.43) | ALDH1A1SMN1; SMN2KDM4ENPSR1LMNA | |
| SCHEMBL8089922 | 0.83 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2KDM4ENPSR1LMNA | |
| SCHEMBL8076752 | 0.83 | MEN1 (0.42) | ALDH1A1SMN1; SMN2KDM4ENPSR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6057447-A | BACTERICIDES FOR CAMPYLOBACTER | ZENYAKU KOGYO KABUSHIKI KAISHA (JP) | 2000-05-02 | — | — | US | disclosed |
| EP-0926139-A1 | QUINOLINE SULFIDE DERIVATIVES | ZENYAKU KOGYO KABUSHIKIKAISHA (JP) | 1999-06-30 | — | — | EP | disclosed |