Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 1/20 | 0.41 |
| ▸ | SSTR4 | P31391 | 2/20 | 0.41 |
| ▸ | CTSC | P53634 | 10/20 | 0.40 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.37 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.37 |
| ▸ | MLNR | O43193 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | ACE | P12821 | 1/20 | 0.36 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8086169 | 0.81 | GNPAT (0.44) | ACE | |
| SCHEMBL7443139 | 0.78 | CTSL (0.48) | — | |
| SCHEMBL8089807 | 0.77 | CTSK (0.54) | — | |
| SCHEMBL7451264 | 0.77 | FAAH (0.43) | — | |
| SCHEMBL7441597 | 0.77 | CTSK (0.54) | — | |
| SCHEMBL7360271 | 0.77 | CTSC (0.53) | GHSRSSTR4CTSCITGB1ITGA4 | |
| SCHEMBL7360264 | 0.77 | CTSC (0.53) | GHSRSSTR4CTSCITGB1ITGA4 | |
| SCHEMBL7438536 | 0.76 | NOS2 (0.48) | CAPN1 | |
| SCHEMBL7607638 | 0.76 | SSTR4 (0.50) | GHSRSSTR4CTSCITGB1ITGA4 | |
| SCHEMBL7446085 | 0.74 | MEN1 (0.53) | CAPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0817795-B1 | NOVEL 4-SUBSTITUTED-3-PEPTIDYL-AZETIDIN-2-ONE DERIVATIVES USEFUL AS CYSTEINE PROTEINASE INHIBITOR | NAEJA PHARMACEUTICAL INC (CA) | 2000-11-15 | — | — | EP | disclosed |
| US-5986108-A | ENZYME INHIBITORS | SYNPHAR LABORATORIES, INC. (CA) | 1999-11-16 | — | — | US | disclosed |