Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.46 |
| ▸ | JUN | P05412 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 2/20 | 0.45 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | VCP | P55072 | 1/20 | 0.44 |
| ▸ | CCR5 | P51681 | 1/20 | 0.43 |
| ▸ | TNFSF11 | O14788 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | LDHA | P00338 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8085708 | 0.90 | PTGS1 (0.58) | PTGS1TSHRPKMRAB9ANPC1 | |
| SCHEMBL5133639 | 0.77 | PTGS1 (0.68) | PTGS1TSHRPKMRAB9ANPC1 | |
| SCHEMBL101653 | 0.77 | PTGS1 (0.68) | PTGS1TSHRRAB9ANPC1NR3C1 | |
| SCHEMBL27792356 | 0.77 | CA2 (0.53) | TSHRNPC1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL27618225 | 0.77 | PTGS1 (0.63) | PTGS1TSHRNR3C1JUNNFKB1 | |
| SCHEMBL3531124 | 0.76 | LMNA (0.47) | TSHRPKMRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL8779397 | 0.76 | PTGS1 (0.66) | PTGS1TSHRNR3C1JUNNFKB1 | |
| SCHEMBL7650416 | 0.76 | PTGS1 (0.66) | PTGS1TSHRPKMRAB9ANPC1 | |
| SCHEMBL20117542 | 0.76 | PTGS1 (0.66) | PTGS1TSHRPKMRAB9ANPC1 | |
| SCHEMBL2352673 | 0.75 | MTNR1A (0.48) | PTGS1TSHRRAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6140310-A | ADMINISTERING AN EFFECTIVE AMOUNT OF PHOSPHORUS PRODRUG IN A MAMMAL FOR TREATING A VIRAL INFECTION | DRUG INNOVATION & DESIGN, INC. (US) | 2000-10-31 | — | — | US | disclosed |
| US-5789608-A | LIPID SOLUBLE; DIFFUSE INTO CELLS AND TISSUE; VIRICIDES, ANTICANCER AGENTS | DRUG INNOVATION AND DESIGN, INC. (US) | 1998-08-04 | — | — | US | disclosed |
| US-5627165-A | ANTIVIRAL AND ANTILEUKEMIA AGENTS | DRUG INNOVATION & DESIGN, INC. (US) | 1997-05-06 | — | — | US | disclosed |
| EP-0533833-B1 | PHOSPHOROUS PRODUGS | GLAZIER ARNOLD (US) | 1995-12-20 | — | — | EP | disclosed |
| EP-0533833-A1 | PHOSPHOROUS PRODRUGS. | GLAZIER ARNOLD (US) | 1993-03-31 | — | — | EP | disclosed |
| WO-1991019721-A1 | PHOSPHOROUS PRODUGS | GLAZIER ARNOLD (US) | 1991-12-26 | — | — | WO | disclosed |