Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALM1 | P0DP23 | 1/20 | 0.55 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | IDH1 | O75874 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | BCL2 | P10415 | 1/20 | 0.40 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.40 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22664060 | 0.90 | CALM1 (0.44) | CALM1MTNR1AMTNR1BTP53LTA4H | |
| SCHEMBL5250636 | 0.89 | MTNR1A (0.56) | CALM1MTNR1AMTNR1BTP53LTA4H | |
| SCHEMBL8096593 | 0.87 | CALM1 (0.50) | CALM1MTNR1AMTNR1BSIGMAR1 | |
| SCHEMBL8092697 | 0.87 | MTNR1A (0.54) | CALM1MTNR1AMTNR1BTP53LTA4H | |
| SCHEMBL6546128 | 0.86 | CALM1 (0.60) | CALM1TP53LTA4HIDH1ATM | |
| SCHEMBL8088663 | 0.85 | KCNH2 (0.51) | CALM1SIGMAR1CYP3A4 | |
| SCHEMBL3697947 | 0.85 | CNR1 (0.41) | CYP3A4 | |
| SCHEMBL8098838 | 0.84 | KCNH2 (0.54) | CALM1SIGMAR1CYP3A4 | |
| SCHEMBL8095497 | 0.84 | KCNH2 (0.54) | CALM1SIGMAR1CYP3A4 | |
| SCHEMBL8100545 | 0.84 | KCNH2 (0.54) | CALM1SIGMAR1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708077-B1 | Diamino compounds and methods for preparing them | CHISSO CORP (JP) | 2000-12-27 | — | — | EP | disclosed |
| US-5663440-A | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1997-09-02 | — | — | US | disclosed |
| EP-0708077-A1 | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1996-04-24 | — | — | EP | disclosed |