Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.46 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.45 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.41 |
| ▸ | HTR3B | O95264 | 1/20 | 0.41 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.41 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8071311 | 0.81 | MEN1 (0.43) | P4HTMGRM4MEN1KMT2AALDH1A1 | |
| SCHEMBL8083748 | 0.79 | EGFR (0.43) | P4HTMMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL8088414 | 0.79 | KMT2A (0.41) | P4HTMMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL8078603 | 0.76 | VNN1 (0.48) | P4HTMMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL8081787 | 0.71 | CNR1 (0.48) | P4HTMMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL8082051 | 0.70 | HCAR3 (0.49) | P4HTMMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL3639325 | 0.69 | P4HTM (0.64) | P4HTMGRM4MEN1KMT2AALDH1A1 | |
| SCHEMBL8086323 | 0.69 | KDM4E (0.54) | P4HTMGRM4MEN1KMT2AALDH1A1 | |
| SCHEMBL8086591 | 0.69 | CNR2 (0.56) | MEN1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL8081028 | 0.69 | HCAR3 (0.51) | P4HTMMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009016088-A1 | THE USE OF BENZAMIDE DERIVATIVES FOR THE TREATMENT OF CNS DISORDERS | F. HOFFMANN-LA ROCHE AG (CH) | 2009-02-05 | — | — | WO | disclosed |