SCHEMBL8087336

SCHEMBL8087336

Nc1ccc(S(=O)(=O)NCC(=CC(=O)O)C(=O)O)c2ccccc12

nearest known ligand 0.49

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
NSD2 O96028 13/20 0.49
FABP4 P15090 3/20 0.39
CCR8 P51685 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL386440 0.83 NSD2 (0.57) NSD2FABP4
SCHEMBL8087332 0.80 HDAC4 (0.53)
SCHEMBL9751654 0.77 NSD2 (0.51) NSD2FABP4CCR8
SCHEMBL1366996 0.73 NSD2 (0.55) NSD2
SCHEMBL3354585 0.72 NSD2 (0.54) NSD2
SCHEMBL8968288 0.71 CYP3A4 (0.61) NSD2
SCHEMBL2013174 0.71 FABP4 (0.71) NSD2FABP4
SCHEMBL11686439 0.70 NSD2 (0.86) NSD2
SCHEMBL11573784 0.70 NSD2 (0.59) NSD2FABP4
SCHEMBL8864869 0.70 NSD2 (0.54) NSD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2000143653-A FLUORESCENCE EMITTING DICARBOXYLIC ACID ANHYDRIDE, ITS PRECURSOR, FLUORESCENCE EMITTING LABELING REAGENT CONTAINING THE SAME ACID ANHYDRIDE AND REVERSIBLE FLUORESCENCE ANALYSIS WITH THE SAME ACID ANHYDRIDE JAPAN SCIENCE & TECHNOLOGY CORP 2000-05-26 JP disclosed