Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HCAR1 | Q9BXC0 | 3/20 | 0.33 |
| ▸ | BCAT2 | O15382 | 3/20 | 0.33 |
| ▸ | BCAT1 | P54687 | 3/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31442417 | 0.85 | HCAR1 (0.40) | KDM4EHTTHCAR1BCAT2BCAT1 | |
| SCHEMBL29575271 | 0.82 | BCAT1 (0.36) | KDM4EHCAR1BCAT2BCAT1AR | |
| SCHEMBL7245230 | 0.78 | BCAT1 (0.55) | BCAT2BCAT1CYP2C9CYP2C19 | |
| SCHEMBL8420147 | 0.74 | BCAT2 (0.41) | HCAR1BCAT2BCAT1 | |
| SCHEMBL8129531 | 0.73 | HCAR1 (0.38) | KDM4EHTTHCAR1ARMEN1 | |
| SCHEMBL8144284 | 0.69 | LMNA (0.45) | HTTHCAR1CYP3A4MAPTTSHR | |
| SCHEMBL7833292 | 0.69 | NOTUM (0.48) | HTTMEN1MAPTTSHRCYP2C19 | |
| SCHEMBL8578733 | 0.68 | AR (0.34) | KDM4EHCAR1BCAT2BCAT1AR | |
| SCHEMBL8574499 | 0.68 | POLB (0.36) | HTTHCAR1AR | |
| SCHEMBL8302671 | 0.67 | POLB (0.45) | HTTMEN1MAPTKMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1051404-A1 | SUBSTITUTED PHENYLURACILS WITH HERBICIDAL EFFECT | BAYER AG (DE) | 2000-11-15 | — | — | EP | disclosed |
| WO-1999038851-A1 | SUBSTITUTED PHENYLURACILS WITH HERBICIDAL EFFECT | BAYER AKTIENGESELLSCHAFT (DE) | 1999-08-05 | — | — | WO | disclosed |