Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7896709 | 0.79 | BCAT2 (0.48) | POLBGAAALDH1A1ATML3MBTL1 | |
| SCHEMBL8574499 | 0.72 | POLB (0.36) | POLBATMHTT | |
| SCHEMBL5858296 | 0.71 | ALDH1A1 (0.52) | POLBGAAALDH1A1ATMRECQL | |
| SCHEMBL8599863 | 0.70 | GAA (0.49) | POLBGAAALDH1A1ATML3MBTL1 | |
| SCHEMBL10701517 | 0.70 | ALDH1A1 (0.51) | POLBGAAALDH1A1ATMRECQL | |
| SCHEMBL10700184 | 0.69 | ALDH1A1 (0.50) | POLBGAAALDH1A1ATMRECQL | |
| SCHEMBL10457648 | 0.69 | ALDH1A1 (0.56) | POLBGAAALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL9683010 | 0.68 | ALDH1A1 (0.49) | POLBGAAALDH1A1ATMRECQL | |
| SCHEMBL9765814 | 0.68 | ALDH1A1 (0.49) | POLBGAAALDH1A1ATML3MBTL1 | |
| SCHEMBL31442417 | 0.68 | HCAR1 (0.40) | GAAMAPTKMT2AMEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999052906-A1 | SUBSTITUTED OXAZOLYLE AND THIAZOLYL URACIL HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1999-10-21 | — | — | WO | disclosed |
| EP-0946544-A1 | HETEROCYCLYLURACIL | BAYER AG (DE) | 1999-10-06 | — | — | EP | disclosed |
| WO-1998027088-A1 | HETEROCYCLYLURACILS | BAYER AKTIENGESELLSCHAFT (DE) | 1998-06-25 | — | — | WO | disclosed |
| WO-1998027082-A1 | HETEROCYCLYLURACIL | BAYER AKTIENGESELLSCHAFT (DE) | 1998-06-25 | — | — | WO | disclosed |