Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | AR | P10275 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.40 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2236313 | 0.72 | KDM4E (0.41) | SMN1; SMN2KDM4EMAPTESR2HSD17B1 | |
| SCHEMBL3789321 | 0.72 | MAOA (0.45) | SMN1; SMN2ALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL11368788 | 0.71 | ALOX5 (0.52) | SMN1; SMN2CYP1A2ALDH1A1NPC1RAB9A | |
| SCHEMBL30603836 | 0.71 | ESR1 (0.71) | SMN1; SMN2CYP1A2ALDH1A1NPC1RAB9A | |
| SCHEMBL30239998 | 0.71 | ESR1 (0.71) | SMN1; SMN2CYP1A2ALDH1A1NPC1RAB9A | |
| SCHEMBL30239993 | 0.71 | ESR1 (0.71) | SMN1; SMN2CYP1A2ALDH1A1NPC1RAB9A | |
| SCHEMBL5013872 | 0.71 | ESR1 (0.71) | SMN1; SMN2CYP1A2ALDH1A1NPC1RAB9A | |
| SCHEMBL239121 | 0.71 | ESR1 (0.71) | SMN1; SMN2CYP1A2ALDH1A1NPC1RAB9A | |
| SCHEMBL15902840 | 0.71 | ESR1 (0.71) | SMN1; SMN2CYP1A2ALDH1A1NPC1RAB9A | |
| SCHEMBL4590239 | 0.69 | RAB9A (0.38) | SMN1; SMN2ALDH1A1NPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6063956-A | APPLYING FUNGICIDE OR INSECTICIDE TO THE LOCUS WHERE CONTROL IS DESIRED | ROHM AND HAAS COMPANY (US) | 2000-05-16 | — | — | US | disclosed |