SCHEMBL2236313

SCHEMBL2236313

Fc1cccc(-c2[c]ccs2)c1

nearest known ligand 0.41

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.41
MEN1 O00255 1/20 0.41
MAPT P10636 1/20 0.41
KMT2A Q03164 1/20 0.41
TAAR1 Q96RJ0 3/20 0.40
ESR2 Q92731 1/20 0.40
HSD17B1 P14061 1/20 0.39
HSD17B2 P37059 1/20 0.39
NISCH Q9Y2I1 1/20 0.38
NOTUM Q6P988 2/20 0.36
IDO1 P14902 2/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
CHRNB4 P30926 1/20 0.34
CHRNA3 P32297 1/20 0.34
TP53 P04637 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28253383 0.78 RAB9A (0.41) KDM4EMEN1MAPTKMT2AIDO1
SCHEMBL3789321 0.78 MAOA (0.45) KDM4EMEN1MAPTKMT2ASMN1; SMN2
SCHEMBL28209751 0.70 CYP2E1 (0.32) MEN1KMT2ASMN1; SMN2TP53
SCHEMBL198702 0.70 TAAR1 (0.68) KDM4EMEN1MAPTKMT2ATAAR1
SCHEMBL29628985 0.67 TAAR1 (0.65) KDM4EMEN1MAPTKMT2ATAAR1
SCHEMBL16605628 0.67 TAAR1 (0.65) KDM4EMEN1MAPTKMT2ATAAR1
SCHEMBL16605626 0.67 TAAR1 (0.65) KDM4EMEN1MAPTKMT2ATAAR1
SCHEMBL177819 0.67
SCHEMBL30172705 0.67 CYP2A6 (0.56) KDM4EMEN1MAPTKMT2ATAAR1
SCHEMBL1205892 0.67 TAAR1 (0.44) KDM4EMEN1MAPTKMT2ATAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115702174-B Production of polypropylene with low volatiles 博里利斯股份公司 2024-05-14 CN disclosed
US-20230331881-A1 PRODUCTION OF POLYPROPYLENE WITH LOW VOLATILES BOREALIS AG (AT) 2023-10-19 US disclosed
CN-114616280-B Heterophasic propylene ethylene copolymer compositions with desirable balance of mechanical properties 北欧化工公司 2023-10-13 CN disclosed
US-20230142911-A1 OLEFIN POLYMERIZATION CATALYST, OLEFIN POLYMERIZATION CATALYST PRODUCTION METHOD, AND OLEFIN POLYMER PRODUCTION METHOD USING THE OLEFIN POLYMERIZATION CATALYST JAPAN POLYPROPYLENE CORPORATION (JP) 2023-05-11 US disclosed
CN-115702174-A Production of polypropylene with low volatiles 博里利斯股份公司 2023-02-14 CN disclosed
EP-4105246-A1 CATALYST FOR OLEFIN POLYMERIZATION, PRODUCTION METHOD FOR CATALYST FOR OLEFIN POLYMERIZATION, AND PRODUCTION METHOD FOR OLEFIN POLYMER USING SAID CATALYST FOR OLEFIN POLYMERIZATION Japan Polypropylene Corporation (JP) 2022-12-21 EP disclosed
US-20220396695-A1 HETEROPHASIC PROPYLENE ETHYLENE COPOLYMER COMPOSITION WITH DESIRABLE BALANCE OF MECHANICAL PROPERTIES BOREALIS AG (AT) 2022-12-15 US disclosed
CN-114616280-A Heterophasic propylene ethylene copolymer compositions having a desirable balance of mechanical properties 北欧化工公司 2022-06-10 CN disclosed
WO-2021254938-A1 PRODUCTION OF POLYPROPYLENE WITH LOW VOLATILES BOREALIS AG (AT) 2021-12-23 WO disclosed
EP-3925986-A1 PRODUCTION OF POLYPROPYLENE WITH LOW VOLATILES Borealis AG (AT) 2021-12-22 EP disclosed
EP-2915816-A1 METALLOCENE COMPLEX AND OLEFIN POLYMERIZATION METHOD Japan Polypropylene Corporation (JP) 2015-09-09 EP disclosed
EP-2562166-B1 5-FLUORO PYRIMIDINE DERIVATIVES AS FUNGICIDES DOW AGROSCIENCES LLC (US) 2015-08-19 EP disclosed
CN-104781270-A Metallocene complexes and olefin polymerization process JAPAN POLYPROPYLENE CORP 2015-07-15 CN disclosed
EP-2360163-B1 METALLOCENE COMPLEX AND METHOD FOR POLYMERIZING OLEFIN JAPAN POLYPROPYLENE CORP (JP) 2014-06-25 EP disclosed
US-8461365-B2 Metallocene complex and polymerization method of olefin JAPAN POLYPROPYLENE CORPORATION (JP) 2013-06-11 US disclosed
CN-102245620-A Metallocene complex and method for polymerizing olefin JAPAN POLYPROPYLENE CORP 2011-11-16 CN disclosed
US-20110230622-A1 METALLOCENE COMPLEX AND POLYMERIZATION METHOD OF OLEFIN JAPAN POLYPROPYLENE CORPORATION (JP) 2011-09-22 US disclosed
EP-2360163-A1 METALLOCENE COMPLEX AND METHOD FOR POLYMERIZING OLEFIN Japan Polypropylene Corporation (JP) 2011-08-24 EP disclosed
EP-1265870-A1 NEW CCR5 MODULATORS: BENZIMIDAZOLES OR BENZOTRIAZOLES AstraZeneca AB (SE) 2002-12-18 EP disclosed
WO-2001066525-A1 NEW CCR5 MODULATORS: BENZIMIDAZOLES OR BENZOTRIAZOLES ASTRAZENECA AB (SE) 2001-09-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110230622-A1 METALLOCENE COMPLEX AND POLYMERIZATION METHOD OF OLEFIN ALOX12, ALOX15, ALOX15B KDM4E 3839/4885MEN1 1018/4885MAPT 2838/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.